Musculoskeletal disease Flashcards
What are some differentials for joint pain in children?
Septic arthritis
Juvenile idiopathic arthritis
Haemophilia
Reactive arthritis
Psoriasis
Trauma
Chrons disease
HSP
What is JIA?
Joint inflammation lasting for 6 weeks for which no other cause is found.
What is the epidemiology of JIA?
1 in 1000 children affected
What is the classification of JIA?
Systemic - Still’s disease - 9%
Polyarticular (>4 joints) 19%
Pauciarticular (<4 joints) - 49%
Spondyarthropathies - 7%
Juvenile psoriatic arthritis - 9%
What is pauciarticular JIA?
The most common type of JIA
Usually affects large joints (knees, ankles, elbows)
Commonly affects girls under 4
Minimal systemic symptoms
What are some biomarkers for pauciarticular JIA?
ANA +VE
RF -ve
What is pauciarticular JIA?
<4 joints affected
What needs to be screened for in children with pauciarticular JIA?
Screen for chronic uveitis
Slit lamp testing
What are some useful tests for joint disease in children?
FBC
ASOT
Rheumatoid factor + ANA
Titers (viral)
Viral titres
ANA
Radiology
Ultrasound
CRP
Aspiration
What is the prognosis of pauciarticular JIA?
80% of cases will resolve
What are the features of polyarticular JIA?
Less common than pauciarticular JIA
Symmetrical involvement of small and large joints
There may be poor weight gain and mild anaemia
Morning stiffness
Irritability in young children
What biomarkers are seen in polyarticular JIA?
ANA +ve
RF -ve
What is the prognosis of polyarticular JIA?
12% develop severe arthritis
Low risk of eye involvement
What is polyarticular JIA?
> 4 joints affected
symmetrical
large and small
TMJ involvement?
What is Still’s disease?
Adult onset Still disease, also known as systemic onset juvenile idiopathic arthritis, is a rare systemic inflammatory disorder characterized by inflammatory polyarthritis, daily fever, and a transient salmon-pink maculopapular rash. A serum ferritin level of more than 1000 ng/ml is common in this condition.