Musculoskeletal Flashcards

1
Q

what does the paraxial mesoderm form

A

Vertebral column + ribs
Dermis of the Back
skeletal muscles

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2
Q

What does the lateral plate somatic mesoderm form

A

Limb bones (scapula clavicle innominate)
dermis of the ventrolateral trunk and limbs
sternum

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3
Q

what is the dosrolateral region
what does it form

A

dermomytome
forms the dermis of the back and muscles of the limbs and trunk

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4
Q

what is the ventromedial region
what does it form

A

sclerotome
forms the vertebral columns and ribs

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5
Q

what type of mesnehcyme is the somite balls oringallly

A

segmented paraxial mesenchyme

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6
Q

where is the Noggin and Sonic the Hedgehog from

A

notochord and neural tube

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7
Q

what moves to surround the notochord and neural tube

A

scletomal

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8
Q

what does dorsal sclertome form Vertebral

A

vertebral arch of the vertebraew

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9
Q

hat does the ventral sclerotome surround the notochord and become

A

vertebral body

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10
Q

how do they form the bone

A

condense and form the cartilage

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11
Q

what is the von ebner’s fissure

A

the divdsion into a cranial and caudal portion of the sclerotome

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12
Q

what forms the annulus fibrousus

A

mesenchyme between the developing vertebrae

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13
Q

what does the notochord form

A

nucleus pulposus

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14
Q

what is the skeletal muscle from

A

paraxial mesoderm

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15
Q

what cells of what migrate ventrally DML + VLL

A

dorsomedial lip and ventrolateral lip of the demomyostome

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16
Q

what does this form

A

dermatome - dermis of the back
myotome - muscle precuros

17
Q

where do some cells also go
why

A

VLL migrate to somatic layer to access developing limbs

18
Q

where does the dermatome migrate

A

ectoderm

19
Q

what does the dermatome join with
to form what

A

and with lateral plate mesoderm forms dermis of the back and limbs

20
Q

what does the myotome differeiante into

A

dorsally epimere
ventrally hypomere

21
Q

what does the epimere do

A

instrinic back muscles (closer to ears)

22
Q

what is this inverated by

A

dorsal rami of the spinal nerves

23
Q

what is the hypomere do

A

lateral and ventral muscles of the thorax and abdomen and limb muscles

24
Q

what is it innverated by

A

ventral rami of spinal nerves

25
Q

where do cells from the hypomere go

A

into developing limb buds

26
Q

what do these divide into

A

anterior and posterior condensations on either side of the develop limb bones

27
Q

what does the anterior condensation forms

A

Upper limb - flexor and pronator muscles
Lower Limb Flexor and adductor muscles

28
Q

what does the posterior condensations form

A

extensor and exntor for upper and lower limb (PEE)
PSA accountment the kind is abdicated - posterior supinator abductor

29
Q

what are the limb buds innverated by

A

primary rami of spinal nerves C5-T1 + L2-S3

30
Q

what do the outpouching of the limbs form

A

ventrolateral body walls

31
Q

what is the lateral plate mesoderm covered by

A

ectoderm

32
Q

what induces the AER

A

lateral plate moderm cell

33
Q

what is the progress zone

A

area of rapidly proliferating mesodermal cells

34
Q

what singal does the WNT7a induce

A

underlying mesenhyme to become dorsal in nature