Muscular system Flashcards

1
Q

Name the 3 types of muscle

A

skeletal
cardiac
smooth

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2
Q

Define the term fascicle

A

A bundle of muscle fibers, multiple fascicles make up a whole muscle

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3
Q

Define epimysium, perimysium, endomysium

A

Epimysium- refers to the outer layer of the muscle which surrounds the whole muscle
Perimysium- refers to the middle layer of the muscle which surrounds the bundle of fibres (fascicles)
Endomysium refers to the inner layer of muscles which surrounds individual muscles fibres

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4
Q

Define & explain the structure of myofibrils

A

Myofibrils are individual muscle fibres, they are made of actin (thin) and myosin (thick) filaments which create a myofilament, the overlap of actin & myosin creates a striated appearance. Account for 80% of cellular volume, made of chains of sarcomeres

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5
Q

Describe characteristics of skeletal muscle

A

Skeletal muscle involves voluntary control (concious), it is striated (many cells), multinucleated, has rapid contractions, but tires easily

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6
Q

Describe characteristics of Cardiac muscle

A

Cardiac muscle is autorhythmic, it contracts automatically, it is a striated muscle with single nuclei, it is heavily branched to ensure the heart contracts as one unit to improve the efficiency of being a pump. It does not fatigue

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7
Q

Describe characteristics of smooth muscle

A

Smooth muscle is involuntary, non-striated and single nucleus, lines the walls of hollow organs e.g., stomach, oesphagus etc, It forces liquids through tubes of the body, also forming valves to regulate the passing of substances. It has no striations and consists of elongated cells which are involved in slow and sustained contractions

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8
Q

Name the functions of muscle

A

Muscle holds us upright & it enables movement (skeletal), it regulates organ volume and moving of substances (smooth)
Contraction of muscles also generates heat, e.g., shivering

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9
Q

Name and explain the 4 characteristics of muscle

A
  1. contractability: the ability to contract when stimulated
  2. excitability: ability to respond to a stimulus
  3. extensibility: the ability to stretch/ extend
  4. elasticity: ability to revert to normal size after contraction/ extension
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10
Q

Define the agonist

A

Contracts to form the movement

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11
Q

Define the antagonist

A

Stretches and yields to the action of the agonist

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12
Q

Define the synergist

A

Contracts to stabilize intermediate joints

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13
Q

Define the fixator

A

Stabilizes the origin of the agonist

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14
Q

Define a sarcomere

A

The region between myofibrils between 2 Z discs, is the smallest contractile unit of a muscle, and contains an A band with an I band at each end, Sarcomeres align side by side

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15
Q

Define a myofilament

A

there are 2 types of contractile myofilaments, they are made up of actin and myosin

Central thick filaments- contain myosin and extend length of band A, connected in the middle by the M line

Lateral thin filaments-contains actin (thin) extend across I bands and into the A band, the Z disc anchors the thin filaments

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16
Q

Explain the structure and function of the sarcoplasmic reticulum

A

a form of SER, It regulates concentraion of calcium. It stores calcium and releases it during muscle stimulation to allow muscle to contract. The SR has lots of mitochondria as well as glycogen granules to provide energy for muscle contraction

17
Q

Explain the structure and function of T tubules

A

T tubules are elongated tubes that are formed by merging of sarcolemma with inferior cell, they are a continuation of the sarcolemma. They have a wide lumen which creates a larger SA for muscle fibres. Their main role is communication, enabling myofibrils to receive signals at the same time and therefore contract simultaneously

18
Q

Define the sliding filament model theory

A

The model states that during contraction, thin filaments (actin) slide over thick filaments (myosin), creating an overlap leading to formation of cross bridges. The length of filaments do not change shape during contraction

19
Q

explain the steps of the sliding filament model

A
  1. The nervous tissue stimulates muscle fibres, AP travels from sarcolemma through T tubules, causing SR to release calcium
  2. Calcium binds to troponin, shifting tropomyosin which exposes binding sites on actin filaments
  3. The myosin heads on the thick filaments bind to the actin binding sites, generating a sliding movement and cross bridges are formed.
  4. cross bridges form and break throughout muscle contraction, propelling movement of filaments into sarcomere
  5. This shortens the muscle cell