Muscles Flashcards

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1
Q

Where is the : A band, I band, H zone and Z line?

A
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2
Q

Where is the A band located? How does this change in contraction?

A

location of myosin [no change in contraction]

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3
Q

Where is the I band located? How does this change in contraction?

A

location between the myosin [shortens in contraction]

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4
Q

Where is the H zone located? How does this change in contraction?

A

location between the actin [shortens in contraction]

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5
Q

Where is the Z line located? How does this change in contraction?

A

end line of sarcomere [moves closer together in contraction]

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6
Q

Role of Ca2+ ions and ATP in muscle contraction?

A
  • Ca2+ ions causes the tropomyosin to move exposing binding sites on actin
  • Ca2+ ions stimulate ATPase
  • ATP causes myosin head to detach
  • ATP releases energy so myosin head returns to original position
  • ATP actively transports Ca2+ ions into sarcoplasmic reticulum when the muscle is relaxed
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7
Q

What occurs in the first part of the sliding filament mechanism?

A
  • the myosin heads pull the actin inwards
  • the somatic motor neurone connects to the skeletal muscle via a neuro-muscular junction
  • one motor neurone connects to a few muscle fibres = motor unit
  • releases acetylcholine that binds to complementary receptors on the muscle fibre membrane (sarcomere)
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8
Q

What occurs in the second part of the sliding filament mechanism?

A
  • Na+ channels open, Na+ ions enter the muscle fibre causing depolarisation
  • wave of depolarisation travels thru sarcoplasmic reticulum
  • causes release of Ca2+ ions into the sarcoplasm
  • this moves the tropomyosin on the actin
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9
Q

What occurs in the third part of the sliding filament mechanism?

A
  • exposes binding sites on the actin
  • myosin heads now bind to the actin (cross bridge)
  • a power stroke occurs, the myosin pulling the actin inwards
  • ATP attaches to myosin head so it detaches
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10
Q

What occurs in the fourth part of the sliding filament mechanism?

A
  • ATP brokendown by ATPase to release energy
  • myosin head goes back to its original position
  • so it reattaches, pulling the actin further inwards
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11
Q

How does fast twitch muscle fibres work?

A
  • provide powerful but short lasting contractions
  • found in biceps and sprinters
  • has thicker myosin
  • contains more enzymes for anaerobic respiration
  • contains phosphocreatine, provides phosphate to ADP to reform ATP
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12
Q

How does slow twitch muscle fibres work?

A
  • provide less powerful but long lasting contractions
  • found in thigh and marathon runners
  • adapted for aerobic respiration
  • has a rich blood supply
  • contains many mitochondria
  • contains glycogen
  • contains myoglobin (stores oxygen)
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