muscles Flashcards

1
Q

Main function of skeletal muscles

A

movements of body

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2
Q

three types of contractile cells of body

A

skeletal, cardiac, smooth muscle cells

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3
Q

Skeletal

A

Elongated
muscle cells are voluntary
Striated

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4
Q

Cardiac

A

branching
involuntary
striated

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5
Q

Smooth Muscle

A

Spindle shaped
involuntary
not striated

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6
Q

Endomysium

A

wrapping around a single cell

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7
Q

aponeurosis

A

broad flat sheet connecting muscles to bones or other muscles

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8
Q

perimyseum

A

wrapping around fascicle

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9
Q

Epimyseum

A

wrapping around an entire muscle

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10
Q

Fascia

A

layers beneath the skin that bind muscles into groups in a body region

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11
Q

Tendon

A

Band or cord that connects muscle to bone

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12
Q

Functions of connective tissue wrappings around and within a skeletal muscle?

A

Insulation, free movement of muscles, carries nerves, blood vessels, fills spaces between muscles

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13
Q

Single Muscle Cell is called:

A

Fiber–basic unit of structure and function for a muscle

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14
Q

Levels of organization from smallest to largest

A
muscle
fascicle
fiber
myofibril
filament
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15
Q

Sarcoplasmic Reticulum

A

Interconnecting tubules of endoplasmic reticulum that surround each myofibril

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16
Q

Sarcolemma

A

Plasma membrane of muscle cell

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17
Q

Sarcoplasm

A

Muscle cell cytoplasm

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18
Q

Sarcomere

A

Region of myofibril between two Z lines

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19
Q

Myofilament

A

Bundle of contractile proteins, arranged into sarcomeres

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20
Q

Fiber

A

Whole muscle Cell

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21
Q

Myofibril

A

threadlike contractile organelle within a muscle cell

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22
Q

T-Tubules

A

An invagination of sarcolemma that projects deep into the muscle cells interior.
Muscle action potential travels through it

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23
Q

Thick filament is made up of:

A

Myosin

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24
Q

Thin filament is made up of:

A

Actin

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25
Regulatory proteins in the thin filament are:
Tropomyosin and Troponin
26
Terminal Cisternae
Sac-like regions of the sarcoplasmic reticulum that contain calcium ions
27
Mitochondrion
Sites of ATP synthesis
28
Triad
A group of one T tubule lying between two adjacent terminal cisternae
29
I Band
Contains only thin filaments
30
A Band
Contains only thick filaments
31
H Zone
Contains both thin and thick filaments
32
Aerobic Exercise
requires warm up sustained for a long period of time used at rest and endurance (ME!)
33
Anaerobic Exercise
Initiated quickly rapid fatigue short, high intensity exercise
34
Twitch
brief single contraction in response to a single stimulus
35
Tone
Small amount of tension in the muscle due to weak contractions of motor units
36
Tetanus
Fusion of twitched to form a smooth sustained contraction
37
Isotonic contraction
Muscle shortens in length/tension remains same during contraction Produces movement
38
Isometric Contraction
muscle length remains about the same/muscle tension increases during contraction maintain upright posture
39
Eccentric Contraction
Muscle lengthens during contraction due to opposite outside force (weights)
40
Electrical Excitability
Ability to respond to certain stimuli by producing electrical signals
41
Conductivity
Signal is allowed to travel
42
How are electrical excitability and conductivity essential for neuron function?
They allow the neuron to generate on action potential and then transfer to other cells
43
Motor Unit
Consists of somatic motor neuron + all the skeletal muscle fibers it stimulates
44
Motor unit recruitment
process where the number of active motor units increases
45
Axon
propagates nerve impulses toward another neuron, a muscle fiber or a gland cell. (threadlike) Conduct and transmit signals to other cells and at the synapse One per neuron, long, have collaterals (branches)
46
Cell body
contains nucleus surrounded by cytoplasm
47
Dendrites
(little trees) Receive info from other cells or outside source (neutron) Receive signals at the synapse Many, short and branched
48
Myelin Sheath
Multi-layered lipid and protein covering around some axons | Insulates and increases speed of nerve impulse conduction
49
What type of glial cell form it in the neurons of the PNS?
Satellite cells
50
What type of glial cell form it in neurons of the CNS?
Neuroglia (glue)
51
Bipolar Neuron
Two processes extending from cell body | limited distribution
52
Unipolar Neuron
``` One process extending from cell body Sensory Neurons (carries incoming info to brain/spinal chord ```
53
Multipolar Neuron
Many interneurons in brain and spinal chord one axon, many dendrites motor neurons
54
Motor Neurons
Conduct electrical signals away from CNS to muscles or glands OUTGOING Efferent neurons Makes up the PNS
55
Sensory Neurons
Conduct electrical signals from receptors to the CNS INCOMING Afferent neurons Makes up the PNS
56
Interneurons
Conducts electrical signals within the CNS Found ONLY in CNS Conducts signals between sensory and motor neurons
57
Steps of muscle contraction
1. Myosin heads hydrolyze ATP and become reoriented and energized 2. Myosin heads bind to actin, forming cross-bridges 3. Myosin cross-bridges rotate toward center of sarcomere (power stroke) 4. As myosin heads bind to ATP, the cross-bridges detach from Actin.
58
What 2 substances must be present for cross bridge cycling to continue
ATP and Calcium
59
What is the function of Calcium Ions in a contraction
triggers exposure of binding sites on actin
60
What is the function of ATP in a contraction?
Binds to cross bridge, energizes myosin heads. Causes the cross bridge to release from Actin
61
What is the function of Cross-bridges?
Flex, pulling the filament inward toward the sarcomere
62
The 3 steps in muscle contraction that require ATP are:
1. Active transport of calcium ions into the SR. 2. Energizes the power stroke of the cross bridge 3. Disconnects the cross bridge from the binding site on the actin at the end of the power stroke.
63
What is "membrane potential"?
Electrical potential difference (voltage) across membrane
64
What is "polarized"?
Separation of Charges across the membrane.
65
Passive or "leak" channels
Open and close randomly but are mostly open
66
Voltage-gated channels
open with electrical stimulus (voltage change)
67
Chemically gated (ligand gated) channels
open when specific molecule binds to it. (bending, pressure.)
68
Characteristics of Na+
Higher concentration along the outside of the cell membrane tends to diffuse INTO the cell, but only to a very limited extent, due to few leak channels moved OUT of the cell by the Na+-K+ pump
69
Characteristics of K+
Higher concentration along the INSIDE of the cell membrane tends to diffuse easily OUT of the cell, due to many leak channels. Moved INTO cell by the Na+-K+ pump
70
Graded potential
Produced when Ligand gated channels open
71
action potential
function of Voltage gated channels in the membrane of axons and neurons (Traveling signal of nervous system)
72
Depolarization
membrane potential becomes smaller; made more positive
73
Hyperpolarization
membrane potential becomes larger
74
Re polarization
Membrane potential is RESTORED to it's resting state
75
A change from -70mV to -85mV is a:
Hyperpolarization
76
A change from -70 mV to -65 mV is a
depolarization
77
Depolarizations are:
Excitatory
78
Hyperpolarizations are:
inhibitory
79
"All or None" principal is:
Once threshold is reached, all action potentials are the same size.
80
Myelinated axons conduct action potentials:
FASTER than unmyelinated axons
81
Axons of larger diameter conduct action potentials:
FASTER than smaller ones
82
Saltatory conduction occurs in
MYELINATED axons
83
List 3 ways in which neurotransmitter molecules can be removed from the synaptic cleft
1) Diffusion 2) Enzymatic degradation 3) Uptake of cells
84
Steps in the synaptic transmission
1--action potential arrives at axon terminal of pre synaptic neuron 2--Voltage-gated Ca^2+ channels open in the axon terminal 3--Calcium diffuses into the axon terminal from the ECF 4--Neurotransmitter is released by exocytosis 5--Neurotransmitter diffuses across the synaptic cell 6--Neurotransmitter molecules bind to receptor molecules in the post-synaptic membrane 7--Ion channels in the post-synaptic membrane are opened 8--a post-synaptic potential is produced 9--Neurotransmitter is removed from the synaptic cleft
85
Components of Reflex Arc
``` 1--Sensory Receptor 2--Sensory Neuron 3--Integrating Center 4--Motor Neuron 5--Effector ```