Muscles Flashcards
3 types of muscles
cardiac
Smooth
Skeletal
What is skeletal muscle
Is attached to the bone via tendon
Incomprensible
Muscles work in pairs-agonist and antagonists
What happens when muscles contract
I band is smaller
H-zone is smaller
Z - lines closer together(sarcomere is smaller)
A-band remains the same
What is myosin
Has a globular head , hinged so it can be more back and forth
Muscle contraction mechanism
First stage
After AP is triggered muscle cell , Ca2+ ions released from sarcoplasmic reticulum into sarcoplasm
Stage 2 muscle contraction
Ca2+ binds to the tropomyosin and causes the protein to change shape which pulls out of the binding site
Stage 3 muscle contraction
Myosin head can now bind to binding site and forms cross bridges
Stage 4 muscle contraction
Myosin head performs the power stroke
Stage 5 muscle contraction
ATP now binds to myosin head hydrolysed by ATP and release energy to break cross bridges myosin head is released and repositioned to attach to another actin binding site
Stage 6 muscle contraction
Cycle repeats as long as there is enough ATP in sarcoplasm but if the muscle stops receiving AP calcium ions detach
What does sarcoplasmic reticulum contain ?
Contains calcium ions
Has bundle of fibres
Muscle cells contain fibres
Myofibril