Muscle Tissue Flashcards
3 muscle types
Skeletal, Cardiac, Smooth
3 ways muscle tissue is classified as
Control( voluntary, involuntary)
Structure (Striated, Non-striated)
Muscle type ( Skeletal, Cardiac, Smooth)
Skeletal muscle tissue is regulated by which branch of the nervous system?
Somatic ( voluntary)
Cardiac and smooth muscle is regulated by which branch of the nervous system?
Autonomic (involuntary)
2 types of muscle structure
Striated & Non-striated
The function of skeletal muscle
Specialised for contractions that produce movement
Voluntary movement of skeleton
Subconscious movement ( Balance/posture)
Describe the histological appearance of skeletal muscle cell (fibres)
Elongated/cylindrical cells, multinucleated cells, main tissue type in skeletal muscle
Skeletal muscle tissue components
Skeletal muscle tissue
Nervous tissue
Blood vessels
Connective tissues
What tissue wraps around the entire muscle?
Epimysium - (dense irregular)
What makes up muscle fibres?
Myofibrils
What repeating units compose myofibrils?
Myofilaments
What is a fasciculi?
Bundles of muscle fibres grouped together
Name the 2 types of myofilaments?
Myosin (Dark thick bands)
Actin (Light thin bands)
What is the name of the contractile unit spanning from z-z lines?
Sarcomeres
What mechanism name allows sarcomere contraction?
Sliding filament mechanism
Individual muscles fibres separated by?
Endomysium
What we call loose connective tissue that surrounds each fascicule?
perimysium
What name is given to a single motor neurone combined with all associated muscle fibres?
motor unit
What is the sarcolemma?
plasma membrane of skeletal muscle.
Describe the features of the sarcolemma?
Invaginates (Pores) into sarcoplasm to form membranous T tubules (Continuous with extracellular space)
What mesh like structure stems from T tubules?
Sarcoplasmic reticulum
What is concentrated within the Sarcoplasmic Reticulum?
Calcium Ions
What is the purpose of the sarcolemma and sarcoplasmic reticulum?
Synchronous contraction of sarcomeres
What is the function of cardiac muscle?
To pump blood through the cardiovascular system, specialised for autonomous contraction
Describe the appearance of cardiac muscle cells
Elongated, branched cylindrical cells, 1 or 2 nuclei (centrally located), striated
Name the 3 layers of the heart wall?
Pericardium (outer)
Myocardium (cardiac muscle tissue)
Endocardium (Single layer of endothelial cells)
What are individual cardiac muscles cells known as?
cardiomyocytes
What type of loose connective tissue is present in cardiac muscle?
Reticular CT - to support rich capillary network
What are intercellular junctions known as in cardiac muscle tissue?
Intercalated disc (Anchor cardiac cells together)
What 2 junction types are found within intercalated discs?
Desmosomes & Gap junctions
Similarities of cardiac muscle with skeletal muscle?
Identical arrangement of sarcomeres
Contain T tubules and sarcoplasmic reticulum
Numerous mitochondria
Glycogen(G) and Lipid (L) granules
Contraction by sliding-filament mechanism
Differences of cardiac muscle with skeletal muscle?
Autonomous (involuntary) contraction
SR – slowly leaks Ca2+
Conducting system
Intercalated discs
What do intercalated discs help to facilitate during contraction?
Allow muscle function as syncytium (Cells working as a single unit)
What allows spontaneous depolarisation in pacemaker cells?
Slow Ca2+ leak
Where is smooth muscle found?
Lining hollow organs
What is smooth muscle specialised for?
Continuous contraction e.g. Peristalsis
Rate of inherent rhythm modulated by
Autonomic nervous stimulation
Hormonal stimulation
Describe the structure of smooth muscle tissue?
Elongated, spindle shaped with tapered ends
Single centrally located nuclei
No sarcomeres
Explain how peristalsis physically works?
Inner circular later constricts lumen diameter
Outer longitudinal layer shorted length
How are actin and myosin arranged in smooth muscle?
Criss-cross lattice
What anchors adjacent cells together?
Dense bodies
What is the third filament type present in smooth muscle?
Desmin
What role does Desmin play in contraction?
Helps to anchor actin to allow myosin to slide over
Skeletal muscle tissue is controlled by which branch of the nervous system?
Autonomic
Parasympathetic
Sympathetic
Somatic
Somatic
Which of the following best describes skeletal muscle cells?
Short,branched fibres with a single nucleus
Elongated, cylindrical fibres with a single nuclei
Smooth tapered fibres with a single nucleus
Elongated, cylindrical fibres with a single nuclei
At rest, non-striated muscle is under control of which branch of the nervous system?
Somatic
Parasympathetic
Sympathetic
Parasympathetic
What name is given to the loose connective tissue surrounding each skeletal muscle fibre?
Epimysium
Perimysium
Sarcolemma
Endomysium
Endomysium
What term describes the contractile unit of skeletal muscle?
sarcolemma
Sarcoplasm
Sarcomere
T tubules
Sarcomere
What connective tissue structure connects skeletal muscle to bone?
Tendon
What feature is shared with both skeletal muscle and cardiac muscle?
Striations
Number of nuclei
Branched structure
Somatic innervation
Striations
What feature is shared between cardiac and smooth muscle tissue?
Branched structure
Number of nuclei
Sarcomerse
Autonomic innervation
Autonomic innervation
In a resting skeletal muscle cell, which specialised structure sequesters calcium?
Sarcolemma
Sarcoplasmic reticulum
Sarcoplasm
Sarcomere
Sarcoplasmic reticulum
T-tubules extend inwards from which specialised skeletal muscle organelle?
Sarcolemma
In which layer of the heart are cardiomycytes located?
Pericardium
Myocardium
Endocardium
Myocardium
Which of the following best describes cardiomyocytes?
branched
cynildcrial
Tapered
branched
Which feature of cardiomyocytes facilitates synchronous contractions
Intercalated discs
Desmosomes
Branchnig
Intercalated discs
which type of muscle tissue functions to propel contents through the gastrointestinal tract?
Smooth
Cardiac
Skeletal
Smooth
What type of myofilament is found only in smooth muscle?
Actin
Myosin
Desmin
Vminient
Desmin
Muscle tissue is specialised to produce what?
contractions
What is the name given to the connective tissue layer that surrounds bundles of muscle fibres, known as fascicles?
perimysium
epimysium
endomysium
perimysium
What is the name given to the connective tissue layer that surrounds individual skeletal muscle fibres?
Perimysium
epimysium
endomysium
endomysium
What name is given to the structure formed by the coming together of the 3 connective tissue layers in skeletal muscle, at the tapering ends?
tendon
The neuronal action potential is converted to which chemical signal, released at the neuromuscular junction?
serotonin
glutamate
adrenaline
acetylcholine
acetylcholine
What structural feature of skeletal muscle fibres propagates action potentials into the interior of the cell?
Myofibrils
Sarcoplasmic reticulum
T-tubules
Sarcomeres
T-tubules
What structural feature of skeletal muscle fibres propagates action potentials into the interior of the cell?
Myofibrils
Sarcoplasmic reticulum
T-tubules
Sarcomeres
T-tubules