Muscle Physiology Flashcards
Which nervous system is responsible for muscle contractions?
Peripheral efferent nervous system -> motor (somatic) nervous system pathway
Skeletal muscle
muscle attached to bone
ATP
Glucose and oxygen help produce, needed for muscle contraction
Creatine phosphate
converts ADP back to ATP for more muscle contractions
Aerobic
needs oxygen
Anaerobic
doesn’t need oxygen
Glucose metabolism steps (3)
1) breakdown of large macromolecules into simple substrates (proteins -> amino acids)
2) breakdown of simple substates into Acetyl CoA, production of limited amount of ATP and NADH
3) complete oxidation of Acetyl Coa to water and CO2, large production of NADH and ATP in mitochondria
Slow-twitch oxidative red muscle
motor unit type 1, smallest in diameter. Posture. oxidative
Oxidative
aerobic metabolism
myoglobin
oxygen binding protein in muscle, gives dark red appearance
fast-twitch oxidative red muscle
motor unit type 2A, standing and walking. Glycolytic
glycolytic
anaerobic metabolism, more oxidative with endurance training
fast-twitch glycolytic white muscle
motor unit type 2B, jumping/sprinting movements. short durations with lots of force. large diameter, glycolytic, pale color
Do oxidative or glycolytic muscle fatigue faster
Glycolytic. produce lactic acid when glycogen supply runs out (burning sensation, slows down activity)
Fascia
connective tissue layers outside of the muscle
3 Types of fascia
epimysium, perimysium, endomysium
Muscle fibers
skeletal muscle cells
sarcolemma
muscle fiber cell membrane (like a plasma membrane)
T-tublues
indentations in the sarcolemma
sarcoplasm
muscle fiber cytoplasm, houses SR
sarcoplasmic reticulum
inside the sarcoplasm, calcium storage compartment needed for muscle contraction
motor units
muscle fiber and all motor neurons that innervate it
myofibril
inside muscle fiber
sarcomeres
inside myofibrils, lined end to end. basic contracting unit of the muscle
actin and myosin
proteins in the sarcomere.
accessory proteins in sarcomere
troponin and tropomyosin. help with contraction and relaxation
Thick myosin filaments (A bands)
heads for attachment to actin
thin actin filaments (I bands)
troponin and tropomyosin proteins, bind to calcium (SR) during contractions
striated appearance due to. . .
light (thin) and dark (thick) bands of a sarcomere
skeletal muscle contraction
actin and myosin forms cross bridges and myosin heads change shape, results in the pulling of thin actin filaments to the middle of the sarcomere