Muscle Pain Flashcards
Myalgia
muscle pain
Myopathy
muscle disease
Myositis
muscle inflammation
cramps
painful, involuntary muscle contraction
contractures
failure of muscles to relax, assoc w/glycolytic and neurologic disease
Etiologies
Range from benign to life-threatening
Dematomyositis and Polymyositis
Immune-mediated inflammatory myopathy; insidious onset of mild myalgias in 25-50% of pts + symmetric, proximal weakness (deltoids, neck, hiops -> difficulty climbing stairs, carrying heavy loads); may p/w dysphagia, ILD, polyarthritis; skin changes seen in DM but no PM
Pyomyositis
Skeletal muscle infection, typically from hematogenous source assoc w/ trauma, HIV, IVDU, malnutrition, most frequently caused by S. aureus
DD of myalgias
Infectious Pain syndromes Rheumatologic Metabolic Endocrine Medications Localized Nocturnal leg cramps
Infectious - Myalgias
Viral (enterovirus, hepatitis, B/C, influenza, dengue, HIV), bacterial (s. aureus, s viridans), spirochetes, necrotizing fasciitis
Pain syndromes - Myalgias
Fibromyalgia, chronic fatigue syndrome
Rheumatologic - Myalgias
PMR, polymyositis/dermatomyositis, RA, SLE, spondyloarthropathy, vasculitis
Metabolic - Myalgias
Scurvy, metabolic myopathy, vit d deficiency
Endocrine - Myalgias
adrenal insufficiency, hypothyroidism, neuropathy
Medications - Myalgias
Statins, antipsychotics, fibrates, colchicine, AZT, cocaine, methadone, labetalol, cimetidine, CsA, cipro, bisphosphonates, aromatase inhibitors, alcohol and antidepressant withdrawal
Localized - Myalgias
Exercise/overus, trauma, pyomyositis, infarction, compartment syndrome, bursitis, necrotizing fasciitis, muscle strain/sprain