Muscle Contraction Flashcards

1
Q

What is the primary role of calcium ions (Ca2+) in muscle contraction?

A

Calcium ions bind to troponin, causing a conformational change that allows myosin to bind to actin.

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2
Q

True or False: ATP is required for muscle contraction.

A

True

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3
Q

Fill in the blank: The stages of muscle contraction include __________, where the muscle fiber generates tension.

A

twitch

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4
Q

What is the role of ATP in muscle contraction?

A

ATP provides energy for the myosin heads to perform the power stroke and is necessary for detaching myosin from actin.

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5
Q

What happens during the relaxation phase of muscle contraction?

A

Calcium ions are pumped back into the sarcoplasmic reticulum, and the muscle fiber returns to its resting state.

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6
Q

What is the first step in muscle contraction?

A

The release of acetylcholine at the neuromuscular junction.

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7
Q

In what structure is calcium stored in muscle cells?

A

Sarcoplasmic reticulum

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8
Q

True or False: Muscle relaxation occurs when calcium ions bind to troponin.

A

False

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9
Q

What is a muscle twitch?

A

A brief contraction and relaxation cycle of a muscle fiber in response to a single stimulus.

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10
Q

What initiates the cross-bridge cycle in muscle contraction?

A

The binding of calcium to troponin.

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11
Q

During muscle contraction, what happens to the sarcomere?

A

The sarcomere shortens as actin filaments slide over myosin filaments.

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12
Q

What is the term for the period of time between stimulus and the beginning of muscle contraction?

A

Latent period

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13
Q

What is the role of myosin in muscle contraction?

A

Myosin heads bind to actin and pull the filaments during the power stroke.

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14
Q

True or False: ATP is not required for muscle relaxation.

A

False

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15
Q

What happens to myosin heads during the power stroke?

A

They pivot and pull the actin filaments toward the center of the sarcomere.

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16
Q

What is the effect of a lack of ATP on muscle contraction?

A

Muscles cannot relax, leading to rigor mortis.

17
Q

Which ion is essential for the exposure of binding sites on actin?

A

Calcium ions (Ca2+)

18
Q

What are the three phases of a muscle twitch?

A

Latent period, contraction phase, and relaxation phase.

19
Q

What occurs during the contraction phase of a muscle twitch?

A

Muscle fibers actively shorten and generate force.

20
Q

Fill in the blank: The primary source of energy for muscle contraction is __________.

A

ATP

21
Q

What is the relationship between calcium and the sarcoplasmic reticulum during contraction?

A

Calcium is released from the sarcoplasmic reticulum into the cytoplasm.

22
Q

True or False: The relaxation phase is longer than the contraction phase in a muscle twitch.

A

True

23
Q

What effect does repeated stimulation have on muscle contraction?

A

It can lead to summation and tetanus, resulting in increased muscle tension.

24
Q

What is the function of troponin in muscle contraction?

A

Troponin binds calcium and regulates the interaction between actin and myosin.

25
Q

During the relaxation phase, which enzyme helps break down acetylcholine?

A

Acetylcholinesterase

26
Q

What is meant by ‘tetanus’ in muscle physiology?

A

A sustained muscle contraction due to rapid, repeated stimulation.