muscle contraction Flashcards

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1
Q

Sliding filament theory

A
  • theory of muscle contraction is the mechanism by which muscles are thought to contract at a cellular level
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2
Q

What is each muscle fibre made up of?

A
  • myofibrils which are smaller fibres
  • contain structures called actin and myosin filaments
  • these filaments slide in and out between each other to form a muscle contraction
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3
Q

structure of a muscle

A

myofibril- a cylindrical organelle running the length of a muscle fibre
- sarcomere - functional unit of myofibril, divided into I, A, and H bands
- Actin - thin contractile protein filament, containing active or binding sites
- myosin - thick, contractile protein filament with protrusions known as myosn heads
-tropomyosin - an actin binding protein that regulates muscle contraction
- troponin - a complex of 3 proteins

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4
Q

steps in muscle contraction
1) nerve impulse

A

-nerve impulse arrives at neuromuscular junction
- causes a release of a chemical
- chemical travels throughout the muscles by transverse tubules
- calcium is then released from sarcoplasmic reticulum as a result of this

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5
Q

transverse tubules

A
  • help to spread electrical impulses throughput the sarcoplasm so they reach all parts of the muscle fibre
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6
Q

2) calcium binds to troponin

A
  • in prescence of high conc of calcium it binds to troponin which changes its shape
    -moves tropomyosin from the active site of the actin
  • myosin filaments attatch to actin filaments which forms a cross bridge that enables contraction
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7
Q

3) ATP breaks down

A

breakdown of ATP releases energy which enables the myosin to pull the actin filaments inwards
-occurs along the entire length of myofibril in the muscle cell

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8
Q

4) Myosin detaches

A

myosin detaches from the actin and cross bridge is broken when an ATP molecule binds to myosin head
-the myosin heads release ADP +P in this process
-

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9
Q

Basic contractile unit of a muscle fibre?

A

the sarcomere
- short unit
- ends are marked with a z line and in the middle is the m line

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10
Q

What membane surrounds the muscle fibre units?

A

sarcolemma
-cell membrane of muscle fibre cells
- bits of the sarcolemma fold inwards across the muscle fibre

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11
Q

Name of the cytoplasm muscle fibres

A

sarcoplasm

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12
Q

mitochondria

A
  • provides ATP that is needed for muscle contraction
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13
Q

sarcoplasmic reticulum

A

stores and releases calcium ions needed for muscle contraction

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14
Q

multinucleate

A
  • when something contains multiple nuclei
  • multiple nuclei help enable skeletal tissue to acquire more oxygen and nutrients while helping the repair of injured muscles
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15
Q

3 types of muscles

A
  • cardiac - only found in the heart, involuntary and contracts and relaxes
  • skeletal - attached to the bones and controls its contractions and relaxations
  • smooth - found in the linings and hollow walls of the organs
    like arteries and veins
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