muscle contraction Flashcards
Sliding filament theory
- theory of muscle contraction is the mechanism by which muscles are thought to contract at a cellular level
What is each muscle fibre made up of?
- myofibrils which are smaller fibres
- contain structures called actin and myosin filaments
- these filaments slide in and out between each other to form a muscle contraction
structure of a muscle
myofibril- a cylindrical organelle running the length of a muscle fibre
- sarcomere - functional unit of myofibril, divided into I, A, and H bands
- Actin - thin contractile protein filament, containing active or binding sites
- myosin - thick, contractile protein filament with protrusions known as myosn heads
-tropomyosin - an actin binding protein that regulates muscle contraction
- troponin - a complex of 3 proteins
steps in muscle contraction
1) nerve impulse
-nerve impulse arrives at neuromuscular junction
- causes a release of a chemical
- chemical travels throughout the muscles by transverse tubules
- calcium is then released from sarcoplasmic reticulum as a result of this
transverse tubules
- help to spread electrical impulses throughput the sarcoplasm so they reach all parts of the muscle fibre
2) calcium binds to troponin
- in prescence of high conc of calcium it binds to troponin which changes its shape
-moves tropomyosin from the active site of the actin - myosin filaments attatch to actin filaments which forms a cross bridge that enables contraction
3) ATP breaks down
breakdown of ATP releases energy which enables the myosin to pull the actin filaments inwards
-occurs along the entire length of myofibril in the muscle cell
4) Myosin detaches
myosin detaches from the actin and cross bridge is broken when an ATP molecule binds to myosin head
-the myosin heads release ADP +P in this process
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Basic contractile unit of a muscle fibre?
the sarcomere
- short unit
- ends are marked with a z line and in the middle is the m line
What membane surrounds the muscle fibre units?
sarcolemma
-cell membrane of muscle fibre cells
- bits of the sarcolemma fold inwards across the muscle fibre
Name of the cytoplasm muscle fibres
sarcoplasm
mitochondria
- provides ATP that is needed for muscle contraction
sarcoplasmic reticulum
stores and releases calcium ions needed for muscle contraction
multinucleate
- when something contains multiple nuclei
- multiple nuclei help enable skeletal tissue to acquire more oxygen and nutrients while helping the repair of injured muscles
3 types of muscles
- cardiac - only found in the heart, involuntary and contracts and relaxes
- skeletal - attached to the bones and controls its contractions and relaxations
- smooth - found in the linings and hollow walls of the organs
like arteries and veins