Muscle Contraction Flashcards
Dendrites
Receives signals from other cells
Cell body
Organizes and keeps the cell functional
Cell membrane
Protects the cell
Axon hillock
Generates impulse in the neuron
Node of Ranvier
Allows diffusion of ions
Schwann Cell
Produces the myelin sheath
Nucleus
Controls the entire neuron
Axon
Transfers signals to other cells and organs
Myelin sheath
Increases the speed of the signal
Axon terminal
Forms junctions with other cells
Muscle contraction
Signal that originate in the CNS are conveyed along nerves (axons) to individual muscle fiber and then along the muscle fiber by electrical activity on the surface of the cells (nerve and muscle) known as Action Potential
Steps to Muscle contraction
1) A nerve impulse travels to the neuromuscular junction on a muscle cell. The neuromuscular junction is the point where the axons of the nerve meet with the muscle cell.
2) Ach is released from the axon to receptors located on the sarcolemma
3) The binding Ach causes depolarization of the sarcolemma by opening ion channels and allowing Na+ ions into the muscle cell.
4) Na+ ions diffuse into the muscle fiber and depolarization occurs.
5) Depolarization creates a wave of action potential (electrical current) across the sarcolemma
6) Action potential travels across the sarcolemma and down the T-tubules which triggers the sarcoplasmic reticulum SR to release Ca+
7) As Ca+ levels rise, Ca+ ions bind with Troponin C which removes the blocking action of Tropomyosin from the Actin binding sites (Troponin I).
8) Myosin is now ready to bind with the actin and form cross bridges which begins the contraction process
9) In order to contract, ATP binds to the Myosin
10) ATP is then hydrolyzed (broken down) to ADP and Pi, which gives the myosin energy to “cock” its head to the high-energy position.
11) The myosin heads then pull the actin filaments inward and release the ADP and Pi .
12) The myosin is now ready for more ATP to bind and repeat the cycle. This process will continue for as long as there are Ca+ ions and ATP available.