Muscle 3 Flashcards

1
Q

T/F Cardiac muscle has a single nucleus at the end of the muscle fiber.

A

False. At the MIDDLE of the muscle fibers

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2
Q

where are intercalated discs

A

at the connections between cells

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3
Q

Desmosomes

A

mechanical connections

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4
Q

Gap junctions

A

eletrical connections

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5
Q

Cardiac muscle works as a __.

A

functional syncytium

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6
Q

T/F Cardiac muscle tissue contracts with neural stimulation.

A

FALSE. without

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7
Q

Timing of contractions in cardiac muscle tissue are determined by these type of cells.

A

Pacemaker cells

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8
Q

The Autonomic nervous system can do what do that cardiac muscle (2)

A

1) alter the rhythmicity established by the pacemaker

2) adjust the contractility of the cardiac muscle

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9
Q

cardiac muscle cell contraction last how much longer than do those of skeletal muscle fibers.

A

10 times

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10
Q

What type of muscle is under control of ANS

A

Smooth

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11
Q

T/F Smooth muscle cells are longer than cardiac muscle cells.

A

TRUE

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12
Q

T/F Cells contain sarcomeres.

A

FALSE

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13
Q

What type of muscle is present in hollow organs and tube structures

A

Smooth

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14
Q

Are smooth muscle cells have a direct connection with neurons?

A

Not exactly. There are places where the plasma membrane is close enough to nerve endings that it can still receive the neurotransmitter and bind to change the activation site

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15
Q

What muscle types behave as a functional syncytium?

A

unitary smooth muscle and cardiac muscle

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16
Q

Cell-to-cell communication occurs through what, as with cardiac muscle?

A

Gap-junction

17
Q

Where does calcium availability for smooth muscle come almost entirely from?

A

extracellular calcium

18
Q

Smooth muscle is MYOSIN/ACTIN regulated.

A

MYOSIN

19
Q

You need MORE/LESS ATP contraction for smooth muscle to occur?

A

LESS

20
Q

What in smooth muscle allows for sustained contractions without much energy consumption?

A

Latch bridges

21
Q

When does relaxation take place in smooth muscle?

A

when Ca++ is taken back up from the cytoplasm and phosphate enzyme inactivates the myosin molecule

22
Q

What activates the myosin light chain kinase?

A

when Ca++ binds to calmodulin

23
Q

What activates the catalytic form of myosin to interact with actin and perform crossbridge cycling? What is needed to keep the cycling occuring?

A

Phosphorylation of myosin light chain kinase;ATP

24
Q

Phasic muscle contraction

A

smooth muscle: twitch like contraction in response to single stimuli or brief bursts of stimuli (occurs in the muscles that propel contents of the organ)

25
Q

What are phasic muscle contractions associated with? (2)

A

1) action potentials

2) slow waves are associated with periodic depolarization and generation of action potentials

26
Q

Tonic muscle contraction

A

smooth muscle: sustained contractions over time

27
Q

Where do tonic muscle contractions occur?

A

In sphincters and blood vessels

28
Q

Why are tonic muscle contractions dissociated with action potentials?

A

Contraction is modulated by external stimuli that modulate membrane potential and calcium availability.

29
Q

T/F Mechanical activity of smooth muscle is constantly modulated by load or length.

A

FALSE. it is not modulated by this, allowing the metabolic demand to be relatively constant.