Muscarinic Antagonist

Question 1

What is the most typical/representative/ famous drug in the category of muscarinic antagonist?

Answer 1

Atropine! Atropine! Atropine!!!

Question 2

How long is atropine’s t1/2?

Answer 2

24-36h

Question 3

____is the most typical drug used in antispasmodic/ antisecretory/ AChE inhibitor OD/ antidiarrheal

Answer 3

Atropine!!!

Question 4

____ is a tropical used drug for ophthalmology for its short term effect

Answer 4

Tropicamide

Question 5

____ is a muscarinic antagonist often used in asthma and COPD

Answer 5

Ipratropium

Question 6

____ is a muscarinic antagonist used in motion sickness

Answer 6

Scopolamine

Question 7

Scopolamine, when used to treat motion sickness, can also cause_____ (side effects)

Answer 7

Sedation/ short-term memory block

Question 8

____ and ____ are used in Parkinsonism/ acute extrapyramidal symptoms induced by antipsychotics

Answer 8

Benztropine/ Trihexyphenidyl

Question 9

___, ___, ___ are the 3Cs of Atropine (actually any muscarinic antagonists)’s side effects

Answer 9

Cardiac toxicity, Coma, Convultion

Question 10

_____ is the treatment of atropine acute intoxication

Answer 10

Physostigmine

Question 11

Name some of the drugs with anti muscarinic pharmacology

Answer 11

Antihistamine/ Tricyclics antidepressants/ Antipsychotic/ Quinidine/ Amantadine/ Meperidine

Question 12

Atropine would cause ___ and ___ of the eyes

Answer 12

Mydriasis/ cycloplegia