Muscarinic Agonists

Question 1

The muscarinic agonists can be categorized into which 2 types?

Answer 1

Direct/ indirect

Question 2

3 typical direct acting cholinomimetics?

Answer 2

Bethanechol/ Methachonline/ Pilocarpine

Question 3

What is the drug for myasthenia Dx?

Answer 3

Edrophonim

Question 4

What is the drug to differentiate myasthenia from cholinergic crisis?

Answer 4

Edrophonium

Question 5

____is used as an antidote in Atropine overdose

Answer 5

Physostigmine

Question 6

Physostigmine can cross BBB due to its _____ structure

Answer 6

Tertiary amine

Question 7

____ is the Rx for myasthenia

Answer 7

Neostigmine

Question 8

____ is the drug for reversal of nondepolarizing NM blockers

Answer 8

Neostigmine/ pyridostigmine

Question 9

_____ is the Rx for Alzheimer’s disease

Answer 9

Donepezil

Question 10

organophosphate is lipid-soluable,_____ inhibitors

Answer 10

Irreversible/ non-competitive

Question 11

____ and ____ are the Rx for insecticides acute toxicity

Answer 11

Atropine, 2-PAM

Question 12

_____ is the treatment for the muscle weakness and sensory loss due to insecticides’ chronic toxicity

Answer 12

Nothing

Question 13

____ is the drug used to treat glaucoma(tropically), xerostomia, and also in screening test for cystic fibrosis(sweat test)

Answer 13

Pilocarpine