Musc Flashcards

1
Q

Anti CCP antibodies

A

Rheumatoid arthritis

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2
Q

Ankylosing spondylitis

A
Buttock/sacroiliac pain, relieved with exercise
Do Shobers test
		○ Anterior uveitis 
		○ Apical lung fibrosis 
		○ Achilles tendinitis 
		○ Amyloidosis
		○ Aortic regurgitation
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3
Q

Anti double-stranded DNA

A

systemic lupus erythematosus

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4
Q

Anti-Jo1 antibodies

A

Polymyositis

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5
Q

Anti-centromere

A

Limited systemic sclerosis

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6
Q

Anti-topoisomerase

A

Diffuse systemic sclerosis (CREST)

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7
Q

cANCA, anti-PR3

A

Wegener’s granulomatosis

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8
Q

α-Endomysial antibody

A

Coeliac disease

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9
Q

Cauda equina causes…

A

flaccid paralysis with loss of reflexes. Sensory and power loss.

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10
Q

Cord compression causes…

A

spastic paralysis with brisk reflexes. Sensory and power loss.

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11
Q

SLE autoantibodies

A

anti dsDNA, ANA and anti cardiolipin

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12
Q

Anti-phospholipid autoantibpdies

A

anti-cardiolipin

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13
Q

anti-topoisomerase II

A

diffuse cutaneous systemic sclerosis

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14
Q

Is there weakness in polmyalgia rheumatica

A

No

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15
Q

Polyarteritis nodosa

A

medium-sized vessel vasculitis

Hep B assosciation

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16
Q

Wegener’s

A

triad of upper resp tract, lower resp tract and kidney bleeds. Saddle nose. cANCA and cavitating lesions on CXR

17
Q

Churg strauss

A

Eosinophilic granulomatosis with polyangiitis

allergic, eosinophilic (tissue damage), vasculitic (organ damage). pANCA

18
Q

Behcet

A

HLA B51
triad of recurrent oral ulcers, genital ulcers and uveitis.
rash, arthritis, pericarditis, colitis

19
Q

Microscopic polyangitis

A

also pANCA

rapidly progressing glomerulonephritis

20
Q

anti_GBM

A

goodpastures. haemoptysis and glomerulonephritis seen

21
Q

What is the definitive diagnosis for polymyositis

A

muscle biopsy