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neurology > Multiple Sclerosis > Flashcards

Multiple Sclerosis Flashcards

1
Q

What is MS?

A

chronic progressive condition that involves demyelination of myelinated neurones in CNS. Oligodendrocytes are targeted.

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2
Q

What causes MS?

A

genetics, EBV, low vitamin D, smoking, obesity

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3
Q

What are the signs and symptoms of MS?

A

optic neuritis, Uhtoff’s phenomenon (symptoms worse in the heat), Lhermitte’s Sogn (electric shock sensation), trigeminal neuralgia, paraesthesia, incontinecne, Bell’s palsy, limb paralysis, spasticity, weakness

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4
Q

What are the sub-types of MS?

A

Relapsing-remitting
Primary progressive
Secondary progressive

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5
Q

How to diagnose MS?

A

MRI (lesions)
Lumbar puncture: oligoclonal bands in CSF
Visual evoked Potentials

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6
Q

How to manage MS?

A

MDT, disease modifying drugs (baclofen, betaferon) and biological therapy, relapses (methylprednisolone)

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neurology (6 decks)

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