Multiple Sclerosis Flashcards
Peak onset of MS
25-35 years old, but can occur at any age
MS affects ___ more than ___
women more than men
patho of MS
autoimmune disease where lymphocytes remain in the CNS and cause inflammation destroying the myelin –> plagues appear on demyelinated areas interrupting the transmission of nerve impulses resulting in neurologic manifestations
MS clinical manifestations depends on ____
which nerves are affected
MS commonly affects -5
- optic nerve
- cerebrum –> cognitive disfunction, changes in memory
- brain stem –> alterations in VS
- cerebellum –> changes in balance and coordination
- spinal cord –> changes in motor and sensory perception
MS follows a ____ ____ pattern
relapsing-remitting
MS clinical manifestations- 13
- visual disturbances
- fatigue
- depression
- numbness
- ataxia
- loss of balance
- spasticity
- bowel and bladder dysfunction
- cognitive dysfunction
- pain
- paresthesia
- speech problems
- dysphagia
MS-assessment and dx-2
- MRI –> shows presence of plaques in CNS
- electrophoresis of CSF –> shows immune system abnormality
Medical Goal for MS
slow progression of disease
DMARDs medications- 4
interferon a/b
glatiramer acetate
methylprednisolone
SE interferon a/b
flu like symptoms
administration interferon a/b
subq
how long does it take to see effects of glatiramer acetate
6 months
how is glatiramer acetate given
sub q
When is methylprednisolone used in MS
for acute relapse
