Multiple Myeloma Flashcards
1
Q
Multiple myeloma excessive which cell
A
Plasma cell
Ineffective monoclonal IgG and IgA
Immunoglobulin fragments ( Kappa and lambda light chain )
2
Q
Risk factors
A
Radiations
MGUS
Petroleum
Pesticides
3
Q
MM symptoms
A
CRAB High Ca Renal abnormality ( Bence jones protein ) Anemia Bone Pain and Lytic lesions in the bone
4
Q
Diagnosis of MM
A
Initial : Serum protein Electrophoresis
Accurate : Bone marrow biopsy
5
Q
Multiple Myeloma Tx
A
70> : Bone marrow transplant
70< : Melphalan “ Alkylating agent “ + Prednisone
