Mullerian Abnormalities CPC

Question 1

Types of Mullein Abnormalities

Answer 1

Lateral or vertical fusion defects

Question 2

Mullerian Agenesis

Answer 2

Absence of most of vagina, cervix, uterus, fallopian tubes
Present with amenorrhea
46XX, normal ovaries, pubic hair and breasts
Associated with renal abnormalities
Normal female testosterone levels, can get pregnant
Treat with vaginal dilator

Question 3

Complete Androgen Insensitivity

Answer 3

Mutation in androgen receptor gene
Present with amenorrhea
XY karyotype with testicular gonads and male testosterone levels
Absent mullerian structures: short vagina, normal breast development

Question 4

Septate Uterus

Answer 4

Present: Miscarriages and preterm deliveries
Uterus cannot support full fetal growth
Rx: Surgical removal of septum

Question 5

Lateral Fusion Defects

Answer 5

Transverse vaginal septums, imperforate hymen, agenesis

Question 6

Vertical Fusion Defects

Answer 6

bicornuate/septate uterus