mucosal immuniy Flashcards
1
Q
How do short chain fatty acids help in our gut layer?
A
SCFA can increase mucus through activating GPR109 A thus producing IL-18 and tightening the junctions by lowering the oxygen level in the cell.
2
Q
What type of goblet cells do we have?
A
- canonical goblet cells
- non-canonical goblet cells
- defence profile goblet cells
- intercrypt goblet cells
3
Q
What is the function of paneth cells?
A
production of AMP (defensin)
4
Q
Do wee have paneth cells in both the large and small intestine?
A
No. the are deep-crypt secretory cells in the large intestine
5
Q
What is SED?
A
Sub-epithelial dome
6
Q
What can mature M-cells produce?
A
Glycoprotein 2+. this binds to the type I on gram-negative like E-coli
