MTB3- Neurology Flashcards
Fqirst step when you’re suspeciouse of TIA?
Head non-contrast CT Scan to R/o hemorrhagic stroke
appraoch to TIA or stroke?
- First step is to take a non contrast head CT to R/o hemorrhagic stroke. If it’s less than 3 hours start theombolytics , if it’s more than 3 hours then start ASA. If the patient is already on ASA switch to Clopidogrel or add Dipyridamole.
Statins for all the patients with non-hemorrhagic stroke.
Contraindications to thrombolytic therapy?
- mass or tumor - cerebral trauma or brain
- Hx of hemorrhagic strokes Surgery within 6 months
- Active bleeding or surgery within 6 weeks - Aortic dissection
- bleeding disorder - CPR within 3 weeks
- stroke within 1 year
Ophtalmic A. Leision?
- Amaurosis Fugas
Tx of cluster headache?
Prophylaxis of cluster headache?
Triptanes + o2
Verapamil
Charactristics of Pseudotumor cerebri?
- pupilledema with NL CT n MRI, headache, double vision ( sixth nerve palsy) , pulsutile tinitus
- Weight loss
- Acetazolamide
- surgery, if it’s not possible then shunt or optic nerve sheath fenestration
How is the management of stroke after non- contrast CT and ASA or thrombolytics?
- find the origine of the stroke:
- echo to fanid vegetations or clot
- ECG holter monitoring( if ECG is NL then Warfarin & dabigartan , Rivaroxaban for atrial fibrilation )
- carotid dopler/ sono=> if there is more than 70 but less than 100 occulosion then end- Artherectomy
- Always consider HTN, DM, Hyperlipidemia
- if the patient is young then: ESR/ AnA / DS DNA/ protein c and s and factor v leiden and anti phospholipid syn. & VDRL/ RPR
Lacunar stroke charactristics?
- absence of cortical deficits - possible bulbar signs
- Ataxia
- Parkinsonian signs
- Sensory deficit
- Hemiparesis
Pos. Inf. cerebral A leision:
- Ipsilateral face
- contralateral body
- vertigo n horner
Pos. Cerebral A. Leision?
Prosopagnosia( inability to recognise faces)
Vertebrobasilar A leision?
1- Vertigo 6- Ataxia
2-Nausea n vomitting 7- bilateral findings
3- drop attack loss of conciousness 8- vertical nystagmus
4- dysarthria n dystonia
5- sensory changes in face and scalp
Ant cerebral A leision?
- profound lower extremity weakness
- mild upper extremity weakness
- urinary incontinence
- Personality change
Middle cerebral A leision?
- upper extremities weakness
- Aphasia
- Apraxia/ Neglect
- eyes deviate toward the leision
- contralateral homonymous Hemianopia
Treatmentof MILD Parkinson’s disease under 60 and over 60?
Under 60 => Benzotropine/Hydroxyzine
Over 60=> Amantadine
1st and 2nd line for long term management of Parkinson?
1st line=> 1- valproic acid 2- Carbamazepine3- Phenytoin4- Levetiracetam 5- maybe Lamotrigine
2nd line=> Gabapantin / Phenobarbital
What med to substitute for Levodopa when there is psychosis with levopdopa?
Quetiapine
When parkinson meds are not effective which med to use?
COMPT inh. Tolcapone/ Entecapone
Mao inh. Selgiline/ Rasagiline
Treatment of severe parkinsonism ?
1- Levodopa carbidopa
2- RPG=> Ropirinole/ pramopaxole/ carbergoline
What is the best initial test to DX MS?
What is the most accurate test to DX MS?
Tx of MS?
- MRI
- MRI/ if not diagnostic then lumbar tap and oligoclonal bands
- steroids/ b- interferone/ glatiramer/ mitoxantrone/ natalizumab/ fingolimod/ dalfapiridine
Diagnostic test for NPH ?
Head CT