MTAP 2 Flashcards
kidney weighs
150g (male)
135 (female)
urethra’s distance
20 cm
3-4 cm
basic functional/ structural unit of the kidney
nephrons
how many nephrons are there
1 - 1.5 millions in one kidney
- seen in cortex alone
- for Tubular Reabsorption and Secretion (removal of wastes)
cortical nephrons
cortical nephrons percentage
85%
cortical nephrons is for
tubular reabsorption and secretion
juxtamedullary nephrons percentage
15%
loop of Henle extends into medulla for the concentration of urine
juxtamedullary nephrons
percentage of cardiac output received by the kidneys
25%
Total Renal Blood Flow
1,200 mL/min
Total Renal Plasma Flow
600-700 mL/min
carries the blood to the glomerulus
Afferent Arterioles
carries blood from the glomerulus
Efferent Arterioles
surround the PCT and DCT
Peritubular Capillaries
- located adjacent to the loops of Henle in
juxtamedullary nephrons - major exchanges of water and salts take place
Vasa Recta
coil of 8 capillary lobes collectively referred as the capillary tuft
Glomerulus
how much is filtered through the glomeruli
120 mL/min, or one-fifth of the renal
plasma
created by the varying sizes of the
arteriole
Hydrostatic Pressure
maintained by the exchange of water
and salts in vasa recta
Osmotic Gradient
the force exerted by albumin and other
proteins in the blood vessels
Oncotic Pressure
repels molecules with NEGATIVE charge due to endothelial cells’ negative charge
Shield of Negativity
which is a smaller size afferent or efferent arteriole
Efferent Arteriole
what is the Glomerular Ultrafiltrate specific gravity
S.G: 1.010
what is the Glomerular Ultrafiltrate pH
pH 7.4
- regulates the flow of blood to and within the glomerulus.
- responds to changes in blood pressure and plasma sodium content.
Renin-Angiotensin-Aldosterone System (RAAS)
It secretes RENIN
Juxtaglomerular Cells
Juxtaglomerular Cells stimulant
Low Blood Pressure
Juxtaglomerular Cells found in
Afferent arteriole
Macula Densa Cells found in
Distal Convoluted Tubule
Macula Densa Cells stimulant
Low Blood Volume
First function to be affected in renal disease
Tubular Reabsorption
Active Transport by PCT
Glucose
Amino acid
Salts
Active Transport by Ascending Loop of Henle
Chloride
Active Transport by DCT
Sodium
Passive Transport by PCT
Water
Urea
Passive Transport by Ascending Loop of Henle
Sodium
Urea
Glucose renal threshold
160-180 mg/dL
Threshold Substances:
Sodium chloride
Amino acids
Potassium
Ascorbic acid
Creatine
when urine glucose is positive while
blood glucose is normal.
Tubular Damage