MT2 - Orthomyxo/influenza Flashcards

1
Q

1) Influenzaviruses have segmented genome

A

T

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2
Q

2) HPAI and LPAI strains differ in the number of basal amino acids in the HA protein

A

T

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3
Q

3) HA protein of influenza viruses is responsible for the attachment to the cell

A

T

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4
Q

4) Antigenic drift means serials of point mutations in the HA and NA genes

A

T

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5
Q

5) The NA protein in the influenza virus is responsible for the release from the infected cells

A

T

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6
Q

6) Enzymatic cleavage of the HA protein is needed for the influenza virus penetration into the cell T

A

T

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7
Q

7) Genetic reassortment of human and animal influenza viruses result in the occurrence of new human influenza strains

A

T

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8
Q

8) Bats have an important role in the epidemiology of influenza

A

F

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9
Q

9) Antigenic shift is behind the influenza pandemics

A

T

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10
Q

10) Influenza viruses are classified into genera by their HA and NA proteins

A

F

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11
Q

11) Influenza causes persistent infection in donkey

A

F

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12
Q

12) The serotype of influenza viruses is determined by their HA and NA proteins

A

T

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13
Q

13) The influenza viruses cause respiratory signs in sea mammals

A

T

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14
Q

15) The bird to human host switch of influenza virus is mediated by swine

A

T

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15
Q

16) The main host of influenza is the swine

A

F

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16
Q

17) In humans inactivated vaccines are used for the immunisation against influenza

A

T

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17
Q

.

A

.

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18
Q

20) Influenzaviruses are sensitive to drying out

A

T

19
Q

21) For the in vitro propagation of influenza viruses embryonated eggs is used

A

T

20
Q

22) The high virulence of some influenza A viruses is the result of mutations in the HA gene

A

T

21
Q

-

A

-

22
Q

24) Dogs are susceptible to horse origin influenza strains

A

T

23
Q

25) The HPAI strains can cause CNS Signs

A

T

24
Q

26) HPAI causes blood vessel damages and generalised infections

A

T

25
Q

27) The HPAI strains are usually developed from the H5 and H7 influenza viruses

A

T

26
Q

28) The LPAI causes immunosuppression

A

T

27
Q

29) Cat is susceptible to human seasonal influenza

A

F

28
Q

30) Swine recovered from influenza should not be kept for breeding

A

T

29
Q

31) Influenza causes high morbidity but low mortality in swine

A

T

30
Q

32) The HPAI causes skin haemorrhages in swine

A

F

31
Q

33) Swine influenza outbreaks occur usually during summer

A

F

32
Q

34) In a horse influenza outbreak all infected horses must be killed

A

F

33
Q

35) The generalized symptoms of horse influenza are result of the interferon response

A

T

34
Q

36) Racehorses should be vaccinated before the influenza season

A

F

35
Q

37) Breeding mares should be vaccinated before the influenza season

A

F

36
Q

38) The eggs produced in LPAI infected flock can be hatched

A

T

37
Q

39) The HPAI infection can be unambiguously differentiated from Newcastle disease by the clinical signs

A

F

38
Q

40) The HPAI strains can cause clinical signs in waterfowl

A

T

39
Q

41) In poultry farms LPAI may be endemic without clinical signs

A

T

40
Q

42) Waterfowl can carry the influenza viruses for long time

A

T

41
Q

Influenza viruses are shed by birds exclusively in the nasal discharge

A

F

42
Q

44) Avian influenza is zoonotic

A

T

43
Q

45) The virulence of avian influenza is determined by the i.v. pathogeny index and mortality

A

T

44
Q

46) Avian influenza can switch directly to human and cause epidemics with high case numbers as result of human to human transmission

A

F