MT2 - Orthomyxo/influenza Flashcards
1) Influenzaviruses have segmented genome
T
2) HPAI and LPAI strains differ in the number of basal amino acids in the HA protein
T
3) HA protein of influenza viruses is responsible for the attachment to the cell
T
4) Antigenic drift means serials of point mutations in the HA and NA genes
T
5) The NA protein in the influenza virus is responsible for the release from the infected cells
T
6) Enzymatic cleavage of the HA protein is needed for the influenza virus penetration into the cell T
T
7) Genetic reassortment of human and animal influenza viruses result in the occurrence of new human influenza strains
T
8) Bats have an important role in the epidemiology of influenza
F
9) Antigenic shift is behind the influenza pandemics
T
10) Influenza viruses are classified into genera by their HA and NA proteins
F
11) Influenza causes persistent infection in donkey
F
12) The serotype of influenza viruses is determined by their HA and NA proteins
T
13) The influenza viruses cause respiratory signs in sea mammals
T
15) The bird to human host switch of influenza virus is mediated by swine
T
16) The main host of influenza is the swine
F
17) In humans inactivated vaccines are used for the immunisation against influenza
T
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20) Influenzaviruses are sensitive to drying out
T
21) For the in vitro propagation of influenza viruses embryonated eggs is used
T
22) The high virulence of some influenza A viruses is the result of mutations in the HA gene
T
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24) Dogs are susceptible to horse origin influenza strains
T
25) The HPAI strains can cause CNS Signs
T
26) HPAI causes blood vessel damages and generalised infections
T
27) The HPAI strains are usually developed from the H5 and H7 influenza viruses
T
28) The LPAI causes immunosuppression
T
29) Cat is susceptible to human seasonal influenza
F
30) Swine recovered from influenza should not be kept for breeding
T
31) Influenza causes high morbidity but low mortality in swine
T
32) The HPAI causes skin haemorrhages in swine
F
33) Swine influenza outbreaks occur usually during summer
F
34) In a horse influenza outbreak all infected horses must be killed
F
35) The generalized symptoms of horse influenza are result of the interferon response
T
36) Racehorses should be vaccinated before the influenza season
F
37) Breeding mares should be vaccinated before the influenza season
F
38) The eggs produced in LPAI infected flock can be hatched
T
39) The HPAI infection can be unambiguously differentiated from Newcastle disease by the clinical signs
F
40) The HPAI strains can cause clinical signs in waterfowl
T
41) In poultry farms LPAI may be endemic without clinical signs
T
42) Waterfowl can carry the influenza viruses for long time
T
Influenza viruses are shed by birds exclusively in the nasal discharge
F
44) Avian influenza is zoonotic
T
45) The virulence of avian influenza is determined by the i.v. pathogeny index and mortality
T
46) Avian influenza can switch directly to human and cause epidemics with high case numbers as result of human to human transmission
F
