MSRA: Liver Disease Flashcards
What medication is used to treat ascites?
Spironolactone
In liver disease, what happens to the clotting profile?
Prolonged clotting time
All clotting factors are low, except for Factor 8
What are the features of spontaneous bacterial peritonitis?
Ascites
Abdominal pain
Fever
What is the most common cause of spontaneous bacterial peritnotitis?
E.coli
What is the management of spontaneous bacterial peritonitits?
IV Cefotaxime
What are the indications for SBP prophylaxis?
Give oral Ciprofloxacin if:
Previous episode of SBP
Protein <15
Chlids-Pugh 9+ or
Hepatorenal syndrome
What is the management of NAFLD as an incidental finding?
ELF = enhanced liver fibrosis blood test to look for advanced fibrosis
What is the first line management of NAFLD?
Diet+Lifestyle/Weight loss
What is the most common cause of hepatocellular carcinoma worldwide?
Hepatitis B
What is the most common cause of hepatocellular carcinoma in Europe?
Hepatitis C
What is the recommended maximum alcohol intake?
For both men and women
No more than 14 units of alcohol in the week, and to be spread out evenly over 3 days or more
Name 2 risk factors for NAFLD?
Obesity
Type 2 Diabetes
What are the key features of a Hepatitis A infection?
Flu-like prodrome
Deranged LFTs
RUQ pain
Tender hepatomegaly
Which patients should be screened for hepatocellular carcinoma?
Cirrhosis secondary to Hep B, C or HH
Men with cirrhosis secondary to alcohol
What LFT ratio is characteristic of alcoholic hepatitis?
AST:ALT>2
