MSRA: Gastric Disease

Question 1

What is the key investigation for pernicious anaemia?

Answer 1

Intrinsic factor antibodies

Question 2

What is the management of GORD?

Answer 2

Trial of full dose PPI for one month

If symptoms return then low dose PPI which relieves symptoms

Question 3

How can we test for presence of H.pylori?

Answer 3

Urea breath test or stool antigen

Question 4

What is the treatment of H.pylori?

Answer 4

7 days
PPI + Amoxicillin + (Clarith or Metro)

Question 5

What is the test of choice for checking h.pylori eradication?

Answer 5

Urea breath test

Question 6

What are the prerequisites for the urea breath test?

Answer 6

No antibiotics in the 4 weeks before
No PPIs in the 2 weeks before

Question 7

Name 4 risk factors for gastric cancer

Answer 7

Pernicious anaemia
Smoking
H. pylori
Blood group A

Question 8

What are the risks of PPIs?

Answer 8

Osteoporosis and fractures
C diff infection

Question 9

When to stop PPIs before endoscopy?

Answer 9

Stop PPIs two weeks before endoscopy

Question 10

Which cancers are associated with H.pylori infection?

Answer 10

Gastric cancer
B lymphoma of MALT tissue