MSRA infectious disease microbiology

Question 1

Chronic infection with Hep B will produce what on hepatitis screen?

Answer 1

Anti-HBc IgG positive
HBsAG positive
AntiHBC-IGM negative
Anti HBS negative

Question 2

what is the difference in markers between acute and chronic hepatitis?

Answer 2

Acute - anti IgM +ve NOT IgG,negative for IgG
HBsAg positive as in chronic hepatitis

Question 3

Immunity following previous infection with Hepatitis would show what?

Answer 3

anti- HBc IgG +ve
Anti HBs - +ve
HBsAg -ve (unlike acute and chronic)

Question 4

vaccination from Hep B would show what?

Answer 4

anti-HBs +ve

Question 5

which vaccines are considered ‘live attenuated vaccines’?

Answer 5

BCG
MMR
Oral polio
Yellow fever
oral typhoid

Question 6

clarithromycin is first line in campylobacter - true or false

Answer 6

True

Question 7

what antibiotic is used in bacterial vaginosis

Answer 7

metronidazole

Question 8

what is the antibiotic of choice in prostatitis?

Answer 8

ciprofloxacin

Question 9

egg shell calcification on chest x ray is associated with what condition

Answer 9

silicosis

Question 10

what test should be done if suspected phaeochromoytoma?

Answer 10

urinary metanephrines

Question 11

BCG is a live attenuated vaccine - true or false

Answer 11

True

Question 12

MMR is a live attenuated vaccine - true or false

Answer 12

True

Question 13

influenza IM is a live attenuated vaccine - true or false

Answer 13

False

Question 14

rabies is a live attenuated vaccine - true or false

Answer 14

False

Question 15

Yellow fever is a live attenuated vaccine - true or false

Answer 15

True

Question 16

what organism can commonly cause pneumonia where a communal water supply is involved?

Answer 16

legionella pneumonia

Question 17

which type of dementia is associated with parkinson ian symptoms

Answer 17

Levy body dementia

Question 18

which type of dementia commonly causes a stepwise deterioration in cognitive function?

Answer 18

vascular dementia

Question 19

what drug treatment should be used in life threatening c diff?

Answer 19

Oral vancomycin + intravenous metronidazole

Question 20

if C diff does not respond to first line vancomycin - what is second line?

Answer 20

Oral fixacomicin

Question 21

what is the drug treatment for latent TB?

Answer 21

• 3 months of isoniazid (with pyridoxine) and rifampicin OR
• 6 months of isoniazid (with pyridoxine)

Question 22

what is the recommended treatment for toxoplasmosis in immunocompetent patients?

Answer 22

No treatment

*if immunocompromised or severe - pyrimethamine + sulphadiazine

Question 23

what organism causes breast abscesses in non lactating women?

Answer 23

Group B streptococcus, Klebsiella pneumonia

Question 24

which drug used for malaria prophylaxis is taken weekly and should be avoided in pts with depression?

Answer 24

Mefloquine

Question 25

which organism causes Croup?

Answer 25

Parainfluenza viruses

Question 26

which virus causes kaposi’s sarcoma?

Answer 26

human herpes virus 8