MSRA: Acute Kidney Injury

Question 1

What is AKI stage 1?

Answer 1

Cr increased 1.5 to 1.9x baseline OR
Cr increases by 26 OR
Urine output less than 0.5ml/kg/hr for 6+ hours

Question 2

What is AKI stage 2?

Answer 2

Cr increased 2.0 to 2.9 x baseline OR
Urine output less than 0.5ml/kg/hr for 12+ hours

Question 3

What are the blood results in rhabdomyolysis?

Answer 3

Acute renal failure
Significantly elevated CK (5x ULN)
Myoglobinuria
Hypocalcaemia
Elevated phosphate (released from myocytes)

Question 4

What is AKI stage 3?

Answer 4

Cr increased 3 x baseline+ OR
Cr increases to 354 OR
Urine output less than 0.3ml/kg/hr for 24+ hours

Question 5

What are the urine sodium results in acute tubular necrosis?

Answer 5

Urine sodium is high (kidney can’t concentrate the urine so sodium is lost)
Low urine osmolality (v. dilute)

Question 6

What are the criteria for detecting AKI?

Answer 6

Increase in Cr by 26 in 48 hours
50% increase in Cr in 7 days
UO less than 0.5ml/kg/hr for 6 hours
In children, eGFR decrease by 25% in 7 days