MSK viva Flashcards

1
Q

Enchondroma v chondrosarc

A
Size
Cortical breach
Endosteal scalloping > 2/3 cortical thickness
Soft tissue beyond bone
Permeative appearance
Outside hands and feet, sarc more common
Bone scan uptake more common if sarc
Age
Pain
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2
Q

Lipoma v liposarc

A

Inhomogeneous with significant soft tissue in the fatty mass - may still be benign but can’t differentiate
Poorly defined adjacent structures
Calcification (present in 11% of lipoma but more common in low-grade sarc)
Infiltration or invasion of mediastinum
Thick (>2mm) / nodular septa, enhancement
Growth
Persisent high T2 on FS T2

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3
Q

Fibrous dysplasia

A
Non-neoplastic congenital
Defective osteoblast differentiation
Fibrous stroma and immature woven bone
Associated with McCune-Albright, Mazabraud, isolated endocrinopathy, mostly hypers
Ribs most common monoostotic
Polyostotic commonly unimelic
Ground glass, well circumscribed, no periosteal reaction. May endosteal scallop.
May be completely lytic or sclerotic
May be bubbly cystic

Rind sign - lesion surrounded by thick sclerotic bone

Shephards crook - coxa vara of proximal femur, classically in FD but non-specific
Heterogeneous MR, increased bone scan uptake
Rare malignant degeneration
Differential: osteofibrous dysplasia / ossifying fibroma and adamantinoma - tibia
Cemento-ossifying fibroma - jaw

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4
Q

Lunate dislocation, perilunate

A

.1 - scapholunate dissociation
2 - perilunate dislocation (majority dorsal - volar rare)
3 - mid-carpal dislocation (triquetrum or lunotriquetral also involved)
4 - lunate dislocation

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5
Q

Stress fractures

A

Fatigue and insufficiency fractures
Neck of 2-4 metatarsals
Anterior tibia
Sclerosis, cortical thickening, periosteal reaction
Increased NM uptake 3 phase, focal, fusiform or oval, non-specific
DD shin splint - posteromedial distal 2/3 of tibia, soleus insertion, normal blood flow and pool, linear delayed uptake

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6
Q

Accessory navicular syndrome

A

.Type 2 accessory navicular (fibrous union to navicular) is painful
MR oedema in both

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7
Q

Meniscal tear

A

Horizontal (parallel to tibial plateau), longitudinal, or radial
Bucket handle is a displaced longitduinal tear
High signal, to articular surface, seen on at least 2 slices
If does not extend to articular surface may just be degeneration (adult) or vascularity (child)
Double PCL sign

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8
Q

Tumoral calcinosis

A
1/3 familial, AD
More common in blacks
Painless periarticular masses
Hip, shoulder, elbow, foot, wrist
Amorphous, multilobulated, cloud-like periarticular calcs.
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9
Q

GLAD, SLAP, ALPSA, Perthes - meanings

A

Glad - glenolabral articular disruption lesion
Slap - superior labral anterior posterior tear
Alpsa - anterior labroligamentous periosteal sleeve avulsion
Perthes - tear to anterior inferior labrum, lifted from glenoid
ABER view makes labral tears more conspicuous on arthrogram (abduction external rotation - hand on head)

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10
Q

Liposclerosing myxofibrous tumour

A

AKA polymorphic fibro-osseous lesion of bone
Rare, benign
Prediliction for intertrochanteric region
Slightly more common in males, 30-40
Geographic lucent lesion, sclerotic margin, matrix calc, mildly expansile, multilocular, fat density component
T1 iso to muscle, T2 some bits of high (myxoid)
May have malignant degeneration to osteosarc
Differential: fibrous dysplasia (less sclerosis), lipoma, ABC (more expansile)

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11
Q

Achondroplasia

A
Narrow foramen magnum
Frontal bossing
Posterior vertebral scalloping
Progressive decrease in interpedicular distance
Short pedicle canal stenosis (along with decreased pedicle distance and superimposed degeneration)
Metaphyseal flaring - trumpet bone
Horizontal acetabular roof
Small iliac wings
Champagne glass pelvic inlet
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12
Q

Jaccoud arthropathy

A

Non-erosive subluxing arthopathy of MCPJs
SLE
Originally described in rheumatic fever

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13
Q

Sacral pelvis

A
SPACE MONGREL
Sarcoma (osteo, chondro)/SC teratoma
Plasmacytoma
ABC
Chordoma
Ependymoma
Mets
Osteomyelitis
Neuroblastoma
GCT
Rectal
Ewings
Lymhoma / leukaemia
Or CAN
Chordoma, chndrosarcoma
ABC, GCT
NF
And always mets, myeloma.
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14
Q

Ankylosing spondylitis

A

Associated with upper lobe predominant interstitial lung disease, and cystic spaces
Symmetric, bilateral SI joint involvement
Vertebral body squaring
Bamboo spine, dagger spine
Shiny corners - healing reactive sclerosis of Ramonos lesions
Romanos - erosion of anterior and posterior edges of vertebral endplates
Andersson - non-infectious spondylodiscitis
Enthesophytes
Spinal ligament ossification

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15
Q

Sacroiliitis

A

Seronegative spondyloarthropatheis
Symmetric - ank spond, IBD
Asymmetric - Reiters, Psoriatic

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16
Q

Osteosarcoma

A

MR for local staging for limb-sparing surgery - skip lesions
CT chest and bone scan for distant staging
Talk about staging…
And types and how malignant…

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17
Q

Achilles tendinopathy / retrocalcaneal bursitis

A

Retrocalcaneal bursitis may be seen in infection, inflammation (arthritis), tendon injury or osis
Decreased lucency in Kager triangle
Often associated with Haglund deformity

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18
Q

Lateral condyle fracture and other paeds elbow patterns

A

Supracondylar 60%
Lateral condyle 10-20%
Medial epicondyle 10%

Lateral condylar fractures mostly non-displaced
Medial - widening of growth plate and soft tissue swelling - comparison with opposite side may be useful

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19
Q

Osteogenesis imperfecta

A

Genetic disorder of collagen type 1 production
Osteoporosis with fragile bones, blue sclera
Most are AD, but with different types, can be AR or sporadic
Mild (1), perinatal lethal (2), progressive deforming (3)

Basilar invagination, wormian bones, platyspondyly, codfish vertebrae, pectus, acetabular protrusio, coxa vara, gracile bones

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20
Q

Diaphyseal aclasis

A

AD with incomplete penetrance in females
Complications: vascular and neural impingement, fracture, bursitis, malignancy,
Cartilage cap >1.5cm suspicious, along with growth and pain after skeletal maturity
Can be sessile or pedunculated

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21
Q

Madelung deformity

A
Premature closure of distal radial physis
Bowed radial shaft, palmar and ulnar tilt of carpus, positive ulnar variance
Associations:
Achondroplasia
Trauma
Idiopathic
Turners
Olliers
Hurlers MPS
Diaphyseal aclasis
Nail-patella (AD, absent nails, hypoplastic pateallae, radial heads/capitella, posterior iliac horns (Fongs prongs)
Leri-Weill (mesomelic dwarfism, AD)
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22
Q

Patella dislocation, MR

A

Lateral dislocation
Medial retinacular injury
Medial patellar and lateral femoral condyle bruising
Sliver sign - intraarticular osteochondral fragment in the knee joint on plaing radiograph

Patealla alta predisposes - long tendon

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23
Q

Peripheral nerve sheath tumour

A

Benign majority
Higher rate of malignancy in association with NF1
Nerve goes in and out of mass
Muscles supplied by nerve may show denervation changes
Split fat sign - fine rind of fat around lesion
Fascicular sign - small ring like structures with peripheral hyperintensity on T2 (fascicles of the nerve)
Target sign (mostly in neurofibroma but also others, High T2 around collagenous stroma)
Imaging unreliable to differentiate malignant and benign - the larger it is the more likely it i malignant, irregular borders and rapid growth

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24
Q

ACL rupture, plain film

A

Lateral sulcus sign - depression on lateral condyle at notch between tibial and patellar articular surfaces (terminal sulcus) - from hyperextension or impaction (this is where there is bone brusing also on MR. The normal depth is <1.5mm)
Segond
Arcuate (fibula tip)
Anterior tibial translocation / anterior drawer

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25
Q

Klippel Feil

A

Two or more non-segmented cervical vertebrae
Female predominant
Associated with Sprengel deformity, renal anomalies (VACTERL)

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26
Q

Sprengel deformity

A

Congenital elevation of scapula

An omovertebral bar is often present (may be fibrous or osseous

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27
Q

UBC

A

Benign lucent intramedullary metaphyseal
(note ABC and GCT are eccentric - and are both posterior element lesions - can have UBC of posterior elements)
Can rarely be seen in talus, calcaneus, iliac wing
Sclerotic margin
May have fallen fragment sign

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28
Q

Ribbon ribs

A
Thinned ribs
NF1
OI
Edwards / trisomy 18
Gorham disease / progressive massive osteolysis
29
Q

Hyperparathyroidism

A
Subperiosteal resorption radial aspects of proximal and middle phalanges of index and middle fingers
Subchondral bone resorption e.g. distal clavicle
Acro-osteolysis
Rugger jersey spine
Brown tumours
Salt and pepper skull
Chondrocalcinosis
Rib notching

Periarticular calcs

30
Q

Osteoid osteoma

A
Bone forming tumour
Painful scoliosis, concave on side of lesion,  in 75% of spinal cases
Central lucent nidus
Surrounding reactive sclerosis
Usually cortical but can appear anywhere
Double density sign on NM
Osteoblastoma >2cm
Variable nidus MR signal - surrounding oedema
31
Q

GCT

A

Wide histo differential so radiology important
Often coexistent ABC (and fluid fluid level)
10% malignant, lung mets have excellent prognosis
May appear aggressive
Knee, distal radius, sacrum, vertebral body\
Only occur with closed growth plate (cf. ABCs), extend to articular surface, eccentric
Solid components enhance - helps differentiate GCT with ABC from just ABC

Narrow zone of transition, without sclerotic rim, metaphyseal lesion extending into epiphysis to articular surface, eccentric, no matrix, cortex may be thinned, may have periosteal reaction, may have soft tissue mass
Areas of low signal on T2 from haemosiderin and fibrosis

32
Q

GCT of tendon sheath

A

=PVNS of tendon
Free movement of tendon within lesions
Localised nodules, low MR signal (haemosiderin)
May cause pressure erosions
Fibroblasts, foamy histiocytes, multinucleate giant cells and inflammatory cells in fibrous stroma
Most commonly in hand
Local recurrence in 10-20%

33
Q

Discitis, pyogenic v TB

A

TB - disc preserved until late. Subligamentous spread. Typically 5-10 vertebrae. Skip lesions. Preferential anterior involvment - gibbus deformity. Posterior elements often involved. May lead to vertebra plana or ivory vertebra. Almost always have bone desctruction at time of imaging. 50% have lung disease. Abscesses common. Psoas abscess may be calcified. Absence of reactive sclerosis or periosteal reaction.

Pyogenic. Starts in discs in children, endplates adults. Rapid loss of height favours pyogenic. Reactive sclerosis. Multilevel in 10%

34
Q

Psoriatic arthritis

A

Distal predominant
Combination of erosion and bone proliferation
Enthesites, pencil-in-cup, subluxations and ankyloses, periostitis, assymetric SI joint involvement, paravertebral ossificaiton and sparing of facet joints.
Ivory phalanx - increased density from periosteal and endosteal proliferation. Unique to PA.

35
Q

Pagets, bone scan

A

Starts in subchondral area and advances into diaphysis. Rarely diaphyseal only - in tibia.
Cotton wool skull (sclerotic), and osteoporosis circumscripta

36
Q

OPLL

A

Asians, men
Associated with DISH, ank spond
May cause cord compression

37
Q

Haemachromatosis v CPPD metacarpals

A

.Haemochromatosis more likely to involve all the joints rather than just 2nd and 3rdd

38
Q

Chest wall lesions

A

.

39
Q

Ivory vertebra

A
Mets (prostate, breast, TCC, carcinoid, mucinous adeno, medullyblastoma, neuroblastoma, lymphoma)
TB
Pagets
Haemangioma, chordoma
Vertebroplasty
40
Q

Calcified discs

A

Ochronosis - nucleus pulposis, begins in lumbar spine and ascends
CPPD, haemachromatosis
HPT
Others

41
Q

Scleroderma

A

Dilated distal 2/3 of oesophagus and leads to Barrets
Hidebound small bowel
Acro-osteolysis
Soft tissue calcification
UIP, occasionally NSIP (something previous has suggested NSIP>UIP)
Severe resorption of 1st CMC joint
Finger tip atrophy and rib contractures
Periarticular osteoporosis, joint space narrowing, erosions

ANA non specific
AntiScl70 / antiDNA topoisomerase antibody highly specific, present in 10-20% (or majority)

42
Q

Acro-osteolysis

A

Terminal: Scleroderma, thermal, Raynauds, HPT, Psoriatic arthritis, infection (leprosy), trauma, Reiters
Drugs - ergotamine, phenytoin

Midshaft - hajdu Cheney, PVC, HPT

43
Q

Chance fracture

A

Flexion distraction, usually upper lumbar

Association with pancreatic, duodenal injury

44
Q

Myositis ossificans

A

Mostly secondary to trauma, but may also occur in paraplegics
Painful enlarging mass
Peripheral well organised mature lamellar bone, intermediate osteoid, central non-ossified cellular (fibroblast) focus)
Histologically similar to osteosarcoma
Calcification 2-6 weeks after appearance. Assumes typical peripheral calc usually around 4 weeks. Becomes smaller and denser with time
Differential of parosteal osteosarc (calc starts centrally), and other sarcs.
Can have fluid fluid level.

45
Q

Labral variants

A

Sublabral foramen - anterosuperiorly, does not extend beyond 3. Separation of labrum from glenoid.
Buford complex - absent anterosuperior labrum, 1-3 o’clock, and thickened (cord-like) middle glenohumeral ligament

46
Q

GLAD, SLAP, ALPSA, Perthes

A

Glenolabral articular disruption - anterior inferior labral tear (forced adduction). Glenoid articular cartilage defect.
Superior labral anterior posterior - superior labrum at biceps insertion
Anterior labroligamentous periosteal sleeve avulsion - similar to a Bankart but labrum does not leave the periosteum
Perthes - anteroinferior labral tear, lifted from glenoid.
ALPSA and Perthes similar but in ALPSA the labrum displaces inferomedially, and inferior glenohumeral ligament bunched up and medially displaced

47
Q

Anterior glenolabral injuries

A
Bankart, bony bankart
ALPSA
Perthes
GLAD
HAGL (humeral avulsion of the glenohumeral ligament - can have GAGLs or midsubstance tears)
Bony HAGL
48
Q

Wormian bones

A
OI
Rickets
Downs
Hajdu Cheney
Kinky hair
Cleidocranial dysostosis
Pyknodysostosis
49
Q

PVNS

A

Histology can look similar to sarcomas, so radiology important
Low signal due to haemosiderin
May be inflammatory or neoplastic (Robbins says neoplastic clonal)
Synovial proliferation. May cause marginal erosions. Differential of synovial chondromatosis on plain film.
Treat with synovectomy
Calcification excludes diagnosis
GRE helps look for haemosiderin
Knee, hip, ankle, shoulder, others

50
Q

Bevelled edge

A

Asymmetric involvement of two layers in skull in LCH

51
Q

Absent distal clavicle

A
Holt Oram (along with radial ray anomaly, and ASD and coarctation)
Cleidocranial dysostosis (along with wormian bones)
52
Q

Scoliosis

A

Convex right thoracic, left lumbar, typical for idiopathic adult scoliosis
(Normal S scoliosis)

53
Q

Bakers cyst

A

Communication between joint capsule and semimembranosus / gastroc bursa
Between medial gastrocnemius and semimemb tendons
Bimodal peak - 4-7, and 35-70

54
Q

Posterior element lesion

A
GCT
Osteoblastoma
TB
ABC
Pagets
Eosinophilic granuloma
55
Q

Brodie abscess

A

Intraosseous abscess, subacute osteomyelitis
Penumbra sign of increased T1 around the abscess.
Tibial metaphysis most common

56
Q

Discoid meniscus

A

Usually lateral
50% bilateral
Prone to tears
3 consecutive slices

57
Q

Fibroxanthoma

A

Fibrous cortical defect <20mm, non-ossifuing fibroma >20mm
Common in the skeletally immature
Heal by adulthood
M:F 2:1
Metaphyseal, corticeal, thin rim of sclerosis

58
Q

Ivory phalanx

A

Psoriatic arthritis

Or Pagets

59
Q

Enchondroma

A

50% in small tubular bones of hands and feet
50% in large tubular bones
Multiple in Olliers and Maffucis
Usually narrow zone of transition, cortical scalloping, rings and arcs
Most are metaphyseal, many are diaphyseal. If epiphyseal more likely chondrosarcoma
May see increased uptake on bone scan

60
Q

ABC

A

Eccentric, metaphyseal adjacent to an unfused growth plate
Expansile, lytic
Can be in spine, sacrum
1/3 secondary to an underlying lesion

61
Q

Hand lesions

A

.

62
Q

Finger tip lesion

A

.

63
Q

Dynamic instability

A

> 3mm change flexion extension

Or >10 degree angle change

64
Q

Basilar invagination

A

Tip of dens > 7mm above Chamberlains line, from hard palate to ospisthion (posterio margin of foramen magnum)
Tip of dens 5mm above McGregor line if can’t see opisthion
Line is from hard palate to most caudal part of occipital curve

65
Q

Insall-Salvati ratio

A

Patella tendon : length of patella
>1.2 in alta
<0.8 in baja

66
Q

Patellar instability

A

Trochlear dysplasia, patella alta, lateralisation of tibial tuberosity

Lateral trochlear inclincation - line along lateral trochlear on topmost slice showing cartilage, and line along posterior femoral condyles. Normal is >11 degrees
Trochlear facet asymmetry - Medial facet should be at least 40% that of lateral (trochlear is on the femur)
Trochlear depth - same plane as asymmetry measurement,
average size of the largest point of facets, minus deepest groove point. Should be >3mm
Patellar translation” Tibial tubercle to trochlear groove distance, parallel to the line through posterior condyles: normal <15mm, abnormal >20mm

67
Q

1st CMCJ

A

OA
Or resorbption in scleroderma, along with soft tissue calc, acro-osteolysis, finger tip atrophy, periarticular osteopaenia, joint space narrowings, erosions

68
Q

Osteochondritis dissecans

A

Knee, capitellum, ankle
Knee typically medial condyle (lateral surface of - 70%)
More rarely other surfaces including patella
Knee bilateral 25%
Elbow more common in throwing sports
Ankle - talar dome
Stage 5 disease is secondary degeneration / OA (surgical staging just goes to 4)

69
Q

Spinal nerve sheath tumours

A

Dumbbell
Target sign more common in neurofibromas - central low signal of collagenous stroma on T2
Schwanommas may occur in NF2
Haemorrhage, fat formation, and cyst formation more common in Schwanomma