MSK Tumours Flashcards

1
Q

What is an osteochondroma

A

Bony outgrowth with cartilaginous cap

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2
Q

Who gets osteochondromas

A

Adolescents

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3
Q

Symptoms of osteochondroma

A

Painless hard lump, can cause impingement

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4
Q

Treatment of osteochondroma

A

Excisions biopsy if growing/causing pain

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5
Q

What is an enchondroma

A

Intramedullary metaphyseal cartilaginous tumour

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6
Q

What causes enchondroma

A

Failure in normal enchondral ossification

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7
Q

Symptoms of enchhondroma

A

Asymptomatic usually incidental finding

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8
Q

Treatment of enchondroma

A

Curretage + bone graft

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9
Q

What is a simple bone cyst

A

Single cavity benign fluid filled cyst in a bone

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10
Q

What causes a simple bone cyst

A

Growth defect in physio

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11
Q

Symptoms, diagnosis and treatment of simple bone cyst

A

Asymptomatic, incidental finding, curettage + bone graft

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12
Q

What is an aneurysmal bone cyst

A

Lots of chambers filled with blood and serum

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13
Q

When do people get aneurysmal bone cysts

A

first 2 decades

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14
Q

What causes aneurysmal bone cysts

A

AVM in metaphysic

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15
Q

XR finding for aneurysmal bone cysts

A

Expansile Lucent lesion with smooth margin

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16
Q

Treatment of aneurysmal bone cysts

A

Curettage + bone graft

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17
Q

What is an osteoclastoma

A

Giant cell tumour in metaphysic

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18
Q

Where are osteoclastomas commonly found

A

Around the knee

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19
Q

Symptoms of osteoclastomas

A

Painful, can cause pathological fracture

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20
Q

XR finding osteoclastoma

A

Soap bubble

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21
Q

Where so osteoclastoma metastasise to

A

Lung

22
Q

Treatment of osteoclastoma

A

Curettage, excision, bone cement to destroy remaining tumour

23
Q

What is fibrous dysplasia

A

Fibrous tissue develops in place of normal bone

24
Q

Who gets fibrous dysplasia

A

Adolescents

25
Q

Treatment of fibrous dysplasia

A

Bisphosphonates

26
Q

What is an osteoid osteoma

A

Small nidus of immature bone around sclerotic bone

27
Q

Who gets osteoid osteoma

A

Young men

28
Q

Symptoms of osteoid osteoma

A

Most common in the appendicular skeleton, proximal femur, diaphysis of long bones + vertebrae
Intense pain worse at night

29
Q

Treatment of osteoid osteoma

A

Aspirin, NSAIDS, can require CT guided ablation

30
Q

What is brown tumours

A

Bone lesion in hyperparathyroidism due to excess osteoclast activity

31
Q

What is osteosarcoma

A

Malignant tumour of cells producing osteoid/mineralised bone

32
Q

Who gets osteosarcoma

A

10-25 males

33
Q

Symptoms of osteosarcoma

A

Painful mass, sudden fracture treated with surgery and chemo

34
Q

What is a chondrosarcoma

A

Malignant tumour producing cartilage

35
Q

Who gets chondrosarcoma

A

Adults over 40

36
Q

What is fibrosarcoma

A

Fibrous malignant primary bone tumours

37
Q

Who gets fibrosarcoma

A

Young adults

38
Q

What is Ewings sarcoma

A

Malignant tumour of endothelial cells BAD

39
Q

Who gets Ewings sarcoma

A

10-20

40
Q

Symptoms of Ewings Sarcoma

A

Mimics infection, night pain, mets to lungs and other bones

41
Q

Diagnosis of Ewings sarcoma

A

Moth eaten pattern of destruction + onion skin appearance of bone formation

42
Q

Treatment of Ewings sarcoma

A

Chemo, surgery (amputation), radiotherapy

43
Q

What is PVNS

A

Giant tell tumour of tendon sheath within a joint, causes joint destruction and OA treated with excision

44
Q

What is leiomyoma

A

Tumour of smooth muscle

45
Q

What is rhabdomyoma

A

Benign tumour of striated muscle, usually cardiac

46
Q

What is pleomorphic sarcoma

A

Malignant tumour of soft tissues that don’t resemble the tissue they originated from DIAGNOSIS OF EXCLUSION, common in thigh

47
Q

What is nodular fasciitis

A

Benign cellular proliferation of fibroblastic and myofibroblastic cells

48
Q

Who gets nodular fasciitis and how does it present

A

Young adults with rapidly growing tender nodule in upper limb

49
Q

What is myositis Ossificans

A

Bone that forms within muscle

50
Q

Who gets myositis ossificans

A

Young athletes with history of trauma

51
Q

How does myositis ossificans present

A

Rapid growing soft swelling that hardens, fever + increased WCC

52
Q

What is Desmond tumour

A

Benign tumour of fibroblasts