MSK Tumours Flashcards

1
Q

What is an osteochondroma

A

Bony outgrowth with cartilaginous cap

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2
Q

Who gets osteochondromas

A

Adolescents

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3
Q

Symptoms of osteochondroma

A

Painless hard lump, can cause impingement

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4
Q

Treatment of osteochondroma

A

Excisions biopsy if growing/causing pain

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5
Q

What is an enchondroma

A

Intramedullary metaphyseal cartilaginous tumour

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6
Q

What causes enchondroma

A

Failure in normal enchondral ossification

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7
Q

Symptoms of enchhondroma

A

Asymptomatic usually incidental finding

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8
Q

Treatment of enchondroma

A

Curretage + bone graft

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9
Q

What is a simple bone cyst

A

Single cavity benign fluid filled cyst in a bone

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10
Q

What causes a simple bone cyst

A

Growth defect in physio

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11
Q

Symptoms, diagnosis and treatment of simple bone cyst

A

Asymptomatic, incidental finding, curettage + bone graft

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12
Q

What is an aneurysmal bone cyst

A

Lots of chambers filled with blood and serum

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13
Q

When do people get aneurysmal bone cysts

A

first 2 decades

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14
Q

What causes aneurysmal bone cysts

A

AVM in metaphysic

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15
Q

XR finding for aneurysmal bone cysts

A

Expansile Lucent lesion with smooth margin

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16
Q

Treatment of aneurysmal bone cysts

A

Curettage + bone graft

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17
Q

What is an osteoclastoma

A

Giant cell tumour in metaphysic

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18
Q

Where are osteoclastomas commonly found

A

Around the knee

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19
Q

Symptoms of osteoclastomas

A

Painful, can cause pathological fracture

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20
Q

XR finding osteoclastoma

A

Soap bubble

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21
Q

Where so osteoclastoma metastasise to

22
Q

Treatment of osteoclastoma

A

Curettage, excision, bone cement to destroy remaining tumour

23
Q

What is fibrous dysplasia

A

Fibrous tissue develops in place of normal bone

24
Q

Who gets fibrous dysplasia

A

Adolescents

25
Treatment of fibrous dysplasia
Bisphosphonates
26
What is an osteoid osteoma
Small nidus of immature bone around sclerotic bone
27
Who gets osteoid osteoma
Young men
28
Symptoms of osteoid osteoma
Most common in the appendicular skeleton, proximal femur, diaphysis of long bones + vertebrae Intense pain worse at night
29
Treatment of osteoid osteoma
Aspirin, NSAIDS, can require CT guided ablation
30
What is brown tumours
Bone lesion in hyperparathyroidism due to excess osteoclast activity
31
What is osteosarcoma
Malignant tumour of cells producing osteoid/mineralised bone
32
Who gets osteosarcoma
10-25 males
33
Symptoms of osteosarcoma
Painful mass, sudden fracture treated with surgery and chemo
34
What is a chondrosarcoma
Malignant tumour producing cartilage
35
Who gets chondrosarcoma
Adults over 40
36
What is fibrosarcoma
Fibrous malignant primary bone tumours
37
Who gets fibrosarcoma
Young adults
38
What is Ewings sarcoma
Malignant tumour of endothelial cells BAD
39
Who gets Ewings sarcoma
10-20
40
Symptoms of Ewings Sarcoma
Mimics infection, night pain, mets to lungs and other bones
41
Diagnosis of Ewings sarcoma
Moth eaten pattern of destruction + onion skin appearance of bone formation
42
Treatment of Ewings sarcoma
Chemo, surgery (amputation), radiotherapy
43
What is PVNS
Giant tell tumour of tendon sheath within a joint, causes joint destruction and OA treated with excision
44
What is leiomyoma
Tumour of smooth muscle
45
What is rhabdomyoma
Benign tumour of striated muscle, usually cardiac
46
What is pleomorphic sarcoma
Malignant tumour of soft tissues that don't resemble the tissue they originated from DIAGNOSIS OF EXCLUSION, common in thigh
47
What is nodular fasciitis
Benign cellular proliferation of fibroblastic and myofibroblastic cells
48
Who gets nodular fasciitis and how does it present
Young adults with rapidly growing tender nodule in upper limb
49
What is myositis Ossificans
Bone that forms within muscle
50
Who gets myositis ossificans
Young athletes with history of trauma
51
How does myositis ossificans present
Rapid growing soft swelling that hardens, fever + increased WCC
52
What is Desmond tumour
Benign tumour of fibroblasts