MSK Treatments Flashcards
Spinal stenosis?
Pain control, PT, steroid injections, decompression laminectomy.
Ankylosing spondylitis?
NSAIDs, PT, TNF inhibitors.
Herniated disc?
NSAIDs, PT, muscle relaxers/oral steroids.
If fails conservative tx, corticosteroid injection.
If pain for >6 wks, laminectomy & discectomy.
Compression fracture?
Orthopedic/neuro consult.
Spondylolysis?
Low grade or symptomatic: Observe
Symptomatic: PT & activity restriction
Acute or failed PT: Bracing
Spondylothisthesis?
Mild: PT and activity restriction.
Severe: Surgery.
Cauda equina?
Call ortho/spine/neuro immediate.
RA?
Exercise, NSAIDs for pain. Corticosteroids if NSAIDs don’t work.
What is the best initial DMARD?
Methotrexate.
Side effects of methotrexate?
GI upset, oral ulcers, mild alopecia, bone marrow suppression (must give WITH folic acid), hepatocellular injury.
Leflunomide?
Alternative to methotrexate or can be used as an adjunct to therapy with a DMARD.
Hydroxychloroquine?
Alternative first line DMARD, but usually not as effective as methotrexate and used in less severe cases
What do pts require of they are on hydroxychloroquine?
Eye exam every 6 months because of risk of visual loss due to retinopathy.
Sulfasalazine?
Alternate first line agent, but less effective than methotrexate.
What do you prescribe if first line agents do not work for RA?
Antitumor necrosis factor (anti-TNF) inhibiting agents (etanercept, infliximab).
Reactive arthritis/Reiter Syndrome?
NSAIDs. If no response, sulfasalazine and immunosuppressive agents like Imuran. NO ABX.
Polyarteritis nodosa?
Glucocorticoids.
Refractory: add cyclophosphamide.
Polymyalgia rheumatica?
Corticosteroids to suppress inflammation.
Polymyositis and Dermatomyositis?
First line: High dose corticosteroid.
If refractory: immunosuppressive agents like methotrexate.
Hydroxychloroquine useful for skin lesions.
Fibromyalgia?
Low intensity exercise.
First Line: Amitriptyline.
For trigger points: Local anesthesia.Also Milnacipran and Pregabalin.
CBT.
Sjorgen Syndrome?
Increase mucosal secretions: Artificial tears to prevent corneal ulcers; Increase fluid intake; sugar free gum; artificial saliva and fluoride treatments.
Cholinergic drugs: Pilocarpine or Cevimeline -> increased secretions
Adverse effects = diaphoresis, flushing, sweating, bradycardia, diarrhea, nausea, vomiting.
Scleroderma?
Treatment is organ-specific: GERD = PPIs Raynaud = vasodilators (CCBs) Severe disease = DMARDS Pulmonary fibrosis: Cyclophosphamide Pulmonary hypertension: Bosentan, Sildenafil
Lupus?
AVOID SUN!
Mild: Hydroxychloroquine w/ or w/o NSAIDS and/or short-term low dose glucocorticoids.
Mod: Hydroxychloroquine plus short-term glucocorticoid therapy. Belimumab (Benlysta)- Usually reserved for active cutaneous or MSK disease unresponsive to glucocorticoids or other immunosuppressive agents.
Severe: High dose glucocorticoids or intermittent IV “pulses” of methylprednisolone with other immunosuppressive agents (Cyclophosphamide, Mycophenolate, Rituximab).
Antiphospholipid syndrome?
Asymptomatic = no treatment
Recurrent thrombosis may require lifelong Warfarin or other type of anticoagulant.
Juvenile (Idiopathic) RA?
First line: NSAIDs
If NSAIDs not effective, Steroids.
PT.
Severe/2nd line: Anakinra, methotrexate, leflunomide.
If ANA positive, routine eye exam every 3 months (b/c uveitis).
Hip dislocation?
Closed reduction over conscious sedation or ORIF surgery.
Hip fracture?
Prophylactic antithrombotic therapy for DVT.
Surgical- ORIF.
Trochanteric bursitis?
Rest & NSAIDs.
Steroid injections.
Surgery as last resort with resection of bursa.
Slipped capital femoral epiphysis (SCFE)?
Non weight bearing w/ crutches followed by internal fixation.
Legg-Calve-Perthes Disease?
Activity restriction (non bearing first) w/ ortho follow up. Revascularization within 2 years. PT. Brace/cast. Surgery in advanced cases.
Femoral Shaft fracture?
Surgery within 24-48 hours with ORIF.
Tibial and fibular fractures?
Nondisplaced and closed: Full leg cast for 4-6 wks then below knee walking cast for another 4-6 wks.
Comminuted or displaced: ORIF.
Popliteal (Baker’s) Cyst?
Ice & NSAIDs.
Intraarticular corticosteroid injection for knee pain and swelling.
If cyst gets large, needle drainage.
Surgical excision for refractory.
LCL and MCL?
Sprained or incompletely torn (Grades 1 or 2): Pain control, PT, RICE, NSAIDs, knee immobilizer. Complete tear (Grade 3): Surgery
ACL?
Surgery in younger athletes.
Conservative vs. surgery.
PCL?
Conservative unless other injuries then surgery.