MSK- OA, Rheum Flashcards

1
Q

narrowing of intervertebral disc spaces with formation of osteophytes

A

OA of spine = Spondylosis

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2
Q

RF assessment of osteoporosis

A
B: background- age, fhx, habits
O: ongoing medical
N: nutrition
E: exercise
S: surgical hx
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3
Q

Who should get bone mineral density screenings?

A

ALL WOMEN >65

postmenopausal with 1+ RF or with fx

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4
Q

what score dx osteoporosis

A

Z score

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5
Q

negative bifringence

A

gout

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6
Q

+ bifringence

rhomboid crystals

A

pseudogout

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7
Q

acute attack of gout tx

prevention tx

A

acute- colchicine, indomethacin, ~prednisone

prevention- allopurinol

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8
Q

RA associated with what genetic component

A

HLA-DR4

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9
Q

Heberdens is changes at

Bouchard is changes at

A

Heberdens= DIP
Bouchard= PIP
goes with OA mostly

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10
Q

bone changes seen in OA

A

osteophytes, joint space narrowing

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11
Q

bone changes seen in RA

A

periarticular erosion

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12
Q

When (OA vs RA) has inflammation and lab changes

A

RA has inflammation and (+) labs

-RF, ESR, anti-CCP, anemia

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13
Q

Most specific lab for RA

A

anti-CCP

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14
Q

which (OA vs RA) has morning stiffness and MC affects the wrist

A

RA

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15
Q

DVT patient that has hx of thrombosis and 2 spontaneous abortions (both 2nd trimester)
w/o
dx
tx

A

Antiphospholipid Antibody Syndrome

ELISA for antiphospholipic atb

tx anticoagulation (Heparin not warfarin)

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16
Q

jaw claudication and vision change

A

GCA

start prednisone, get bx within 48 hrs

17
Q

GCA associated with what other Rheum disorder

A

Polymyalgia Rheumatica

18
Q

aching and stiffness of shoulders, neck, and hip-girdle areas that is worse in the morning
dx
tx

A

PR

prednisone-should show rapid response

19
Q

necrotizing inflamm of muscular arterioles and medium sized arteries that spares the capillaries and has no venous involvement or lung involvement

A

Polyarteritis Nodosa

20
Q

60 y/o F who owns a daycare presents with myalgias. On exam you note tachycardia, a mild fever, and a lace-like purple mottled skin that doesn’t blanch (livedo racemosa)
w/o
tx

A

Polyarteritis Nodosa

check for Hep B

can do tissue bx or angio that demonstrates microaneurysms

tx- steroids (prednisone, methylpred)

21
Q

proximal progressive and symmetric muscle weakness
pt has difficulty rising from chair
only other PMH is Raynauds
muscle bx is nl

A

Polymyositis

22
Q

anti-DNA and anti-Smith

A

SLE

23
Q

anti-centromere

antitoposiomerase/ anti-scl-70 atbs

A

Systemic sclerosis (scleroderma)

24
Q

anti-Ro/SS-A
anti- La/SS-B
Elevated ESR, nl CRP, +ANA

A

Sjogren Syndrome

25
Q

lab most specific for Sjorgren’s

A

anti-La