MSK Malignancy Flashcards
Examples of Benign bone tumours
Osteoblastoma Osteoma Giant cell tumour Osteoid osteoma Enchondroma Osteochondroma
Where would you find an osteoblastoma
Vertebrae
similar to osteoid osteoma
Where would you find an osteoma
Skull
associated with Gardner’s syndrome, associated with APC gene on chromosome 5
Where would you find a giant cell tumour
Epiphysis (long bones)
Soap bubble appearance
Where would you find an osteoid osteoma
Femur and tibia
Phalanges and vertebrae
Where would you find an enchondroma
Intramedullary bone
seen in phalanges
How would you best differentiate an osteoid osteoma
Intracortical lesion best differentiated on CT
Nidus
What is an enchondroma
cartilaginous neoplasm
Where would you find an osteochondroma
Metaphysis (long bones)
What is most common benign bone lesion
Osteochondroma
Examples of malignant bone tumours
Osteosarcoma
Chondrosarcoma
Ewing’s sarcoma
Where would you find an osteosarcoma
Metaphysis (long bones)
Risk factors of osteosarcoma
Paget’s disease
Radiation
Familial retinoblastoma
Predominance in children
Bimodal
What is meant by osteosarcoma being bimodal
75% <20 years
Increased >60 years
Location of chondrosarcoma
Medullary cavity of femur, humerus, tibia, pelvis, scapula, spine, skull and craniofacial area