MSK Lab Medicine Flashcards
What is specificity
Ability to correctly identify those WITH disease
What is the true negative rate for a test that has 90% specificity
90%
What is sensitivity
Ability to correctly identify those WITHOUT disease
What is the positivity rate if the sensitivity is 90%
90%
What two results can you have with sensitivity
True positive and false negative
What results can you have with specificity
True negative
False positive
What is SPIN
Specificity
Specific Tests, when Positive, rule disease In
What is SNOUT
Sensitivity
Sensitive tests, when Negative, rule disease Out
What is accuracy
Measure of closeness to the true value (to correctly measure what we intend it to measure)
What is precision
Measure of reproducibility of the test
What is the reference range
Normal range of lab tests
Can be dependent on patient (age, gender,liver, or kidney function
What is the critical value
The panic value
Requires urgent intervention
What does stratum mean
immediately
How fast do STAT labs result
45-90 min
When is point of care testing used
Used for real time decision making
What does APR stand for
Acute Phase Reactants
What is more specific than ESR and CRP
procalcitonin
What metabolic dysfunction disorders may lead to elevated CRP
PCOS and diabetes
Which inflammatory marker test picks up RA
ESR more so than CRP
What is a traditional CRP value
<1mg/dL or <10mg/L
What CRP value is highly suggestive of bacterial infection
> 10mg/dl or 100mg/L
What ESR level is highly suggestive of a bacterial infection
> 100mm/h
Which inflammatory marker is easily impacted by pro-inflammatory states
ESR
What does ESR measure
The speed at which the RBCs fall
