MSK-Derm Health and Society Flashcards

1
Q

What is the difference between pharma and biotech?

A
  • Pharma
    • Large companies w/shareholder financing
    • Usually small molecule druge
  • Biotech
    • Smaller companies
    • Role of venture capital
    • Generally higher molecular weight products made with or from live cells/organisms
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2
Q

What happened 20 years ago that may have contributed to the current opioid epidemic?

A
  • FDA approved the first long-acting/extended release opioid (oxycontin)
  • Consensus statements supported the use of opioids for non-cancer pain
  • Accredidation mandates for monitoring and addressing pain
    • Patient satisfaction surveys: “Did your doctor do everything they could to manage your pain?”
    • Did not mandate opioid prescription, but mandate in conjunction with consensus statemetnets + availability -> increased prescription
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3
Q

____ of the population age 16 years and older had proficient health literacy

A

12% of the population age 16 years and older had proficient health literacy

  • This highlights the need for patient-education as a part of care
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4
Q

What is conservative prescribing?

Descrbe the strategies

A

Do not prescribe unnecessary medications

  • Think beyond drugs
  • Practice strategic prescribing
  • Maintain awarenes and vigalence regarding adverse effects
  • Be skeptical and cautious of new drugs
  • Work with patients to establish a deliberative shared agenda
  • Consider long-term, broad effects of a treatment course

Especially impoartant in elderly patients

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5
Q

Respecting a patient’s customs and language preferenes is an example of which quadrant of the patient-centered education model?

A

Cultural respect

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6
Q

What was the sunshine act?

A

The act that mandated that pharmaceutical industry payments to physicians be disclosed to the public

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7
Q

What is the 340B discount program?

A

A program to increase access to medications for low-income hospitals and communities

  • Drug manufacturer cells outpatient drugs to 340B hospitals at discount prices
    • Only hostpitals with high volumes of low-income patients, or serve rural areas qualify
  • Low incompe patients get the medication free or at a reduced cost
  • Insured patients pay their normal copay

The hospital saves money by buying the drugs at the discounted price from the manufacturer

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8
Q

Which region of the United States has the highest rates of benzodiazepine use in conjunction with opioids?

A

The South

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9
Q

Which state has the death rate due to opioid overdose?

A

West Virginia

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10
Q

Which states had the highest use of high-dose opioid pain relievers?

A

Delaware, Tenessee, Nevada

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11
Q

What may lead to high variability between opioid prescription rates by state/region?

A

Lack of consensus on indications for use

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12
Q

What are the 5 key points from the 2011 IOM briefing pain management?

A
  1. Heighten awareness about pain and its health consequences
  2. Emphasize the prevention of pain
  3. Improve pain assessment and management in the delivery of healthcare and financing programs of the fed. govt
  4. Use public health communication strategies to inform patients on how to manage their own pain
  5. Address disparities in the experience of pain among subgroups of Americans
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13
Q

Which state has the highest rates for opioid prescriptions? Which state has the lowest?

A

Highest – Alabama

Lowest – Hawaii

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14
Q

What are the strategies for primary, secondary, and tertiary prevention of opioid addiction and related death?

A
  • Primary
    • Educate and legislate physicins to follow treatment guidelines
    • Develop more abuse-deterrent LA/ER opioids
    • Develop guidelines for prescribing OPRs in the ER
  • Secondary
    • Identify and direct to treatement early
  • Tertiary
    • Ensure access to effective treatment
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15
Q

Which age group has the highest risk of overdose death?

A

45-54 year olds

  • Nonmedical use most common in 15-24 year olds
  • 55-64 year old overdose rate is rising most quickly
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16
Q

Summarize the house drug pricing bill passed in 2019

A
  • The government will play a larger role in negotiating medicare part D drugs
  • Limits to the ability of drug manufacturers to annually hike prices in medicare
  • Limit to out-of-pocket drug costs for medicare beneficiaries

Result:
Lower federal spending by 456 billion, but Pharma will launch fewer drugs

8 fewer in the 1st decade, 30 fewer in the next; lost pharmaceutical revenue will eat into R&D

17
Q

What are the IOM 6 aims of patient-centered educaation?

A
  • Safe
    • Teach proper technique
    • Make sure pt. understands the “why” of each component fo a task
  • Effective
    • Find the best, most up to date method for that patient
  • Efficient
    • Useful, cost-effective
    • Group sessions, peer mentor if appropriate
  • Timely
    • Education occurs when pt and family can fully engage in learning
    • Consider time of day, chunking information
  • Patient-centered
    • Learning style, consider pt preferences
  • Equitable
    • All pts receive health education
18
Q

What are the negative impacts (unintended consequences) of changes to opioids intended to deter abuse?

A

Increase in heroin-related cases and heroin treatment admissions

19
Q

Which states had the highest use of long-acting/extended release opioid pain relievers?

A

Maine, Delaware, New Hampshire

20
Q

How do most people get ahold of opioids for non-medical use?

A

Given by a friend for free

Prescribed by more than one physician is also common

21
Q

What are the quadrants of the patient-centered education model?

A
  • Cultural Respect
  • Health Literacy
  • Patient-Provider Partnership
  • IOM 6 aims
    • Safe
    • Effective
    • Efficient
    • Timely
    • Patient-centered
    • Equitable

E Wojciechowski, L Rosen. Case Review: Journey for Developing a Patient-Centered Education Model. The Internet Journal of Advanced Nursing Practice. 2018 Volume 17 Number 1.

22
Q

What are the two major goals of the patient-centered education model?

A

Improve patient quality of life

Reduce hospital readmissions

23
Q

What are the 3 overarching principles for combating the opioid crisis?

A
  • More education
  • More monitoring
  • Interdisciplinary treatment of pain
    • Leverage non-opioid options
24
Q

What is the first thing prescribers and patients should discuss when adding a new medication?

A

The purpose of the medication and the expected benefits and potential risks

25
Q

Which states had the highest use of opioid pain relievers?

A

Alabama, Tenessee, West Virginia

26
Q

What is high-value prescribing?

A

Provide the simplest medication regimen that minimizes physical and financial risk while achieving the best outcome

27
Q

Which drugs are most profitable for pharmaceutical companies?

A

Cancer drugs

28
Q

Why is it dangerous to use opioids and benzodiazepines together?

A

Increased risk of respiratory depression

29
Q

The Beers and STOPP criteria can be used…

A

As part of the medication review of elderly patients

30
Q

Which state has the highest rates for benzodiazepine prescriptions?

Which state has the lowest?

A

Highest - West Virginia

Lowest – Hawaii