MSK

Question 1

Bone resorption and sclerotic changes with normal calcium and an elvated ALP is suggestive of what disease?

Answer 1

Paget’s disease

Question 2

Common presenting symptoms of Paget’s disease of the bones?

Answer 2

Paget’s disease usually affects:

Skull (large head, hearing difficulties, headache)

femur (bowing and asymmetry leading to osteoarthritis and chalkstick fractures)

pelvis

Spinal stenosis and back pain