MSK

Question 1

What is a Charcot joint?

Answer 1

Due to neurogenic arthropathy (e.g. B12 deficiency, diabetes, peripheral nerve damage, spinal cord injury, etc.) Causes deformed joints due to lack of sensation and neurogenic feedback. This leads to arthritis, fractures, and signs of degenerative joint disease and loose bodies on imaging. Can treat with mechanical devices

Question 2

What disease is pes anserinus pain syndrome (aka anserine bursitis) associated with?

Answer 2

Diabetes

Question 3

What is Felty syndrome?

Answer 3

RA (severe joint disease, rheumatoid nodules, vasculitis [mononeuritis multiplex, necrotizing skin lesions]) + neutropenia (ANC <1500/uL) + splenomegaly

Question 4

What is the initial diagnostic modality of choice for suspected osteomyelitis of the spine?

Answer 4

MRI

Question 5

What are lab values indicative of Paget disease of bone?

Answer 5

• Elevated alkaline phosphatase
• Elevated bone turnover markers (eg procollagen type I N-terminal propeptide [PINP], urine hydroxyproline)
• Normal serum calcium and phosphorus

Question 6

What is treatment for Paget disease of bone?

Answer 6

Bisphosphonates

Question 7

What is hypertrophic osteoarthropathy?

Answer 7

Condition where digital clubbing is accompanied by sudeen-onset arthropathy (usually affecting the wrist and hand joints). Hypertrophic pulmonary osteoarthropathy is a subset that can be attributed to underlying lung disease (e.g. lung cancer, TB, bronchiectasis, or COPD)

Question 8

What provocative maneuver elicits pain in avascular necrosis?

Answer 8

Hip abduction and internal rotation

Question 9

What duration of sx do pt’s need usually for a dx of RA?

Answer 9

At least 6 weeks

Question 10

What are the primary signs and symptoms of ankylosing spondylitis?

Answer 10

Low back pain that improves with exercise, hip & buttock pain, limited chest expansion & spinal mobility, enthesitis (inflammation at the site of insertion of a tendon to the bone), systemic symptoms (e.g. fevers, chills, fatigue, weight loss), and acute anterior uveitis (unilateral pain, photophobia, blurry vision)

Question 11

What are secondary causes of pseudogout?

Answer 11

Hyperparathyroidism, hypothyroidism, and hemochromatosis

Question 12

What are features that can be seen in the hands in patients with psoriatic arthritis?

Answer 12

Affects distal interphalangeal joints, arthritis mutilans (deforming arthritis), dactylitis (sausage digitis), nail pitting and onccholysis.

Question 13

What serum marker is elevated in hypothyroid myopathy?

Answer 13

CK