MSK Flashcards
Cloudy fluid, blue crystals
Calcium Pyrophosphate Deposition (CPPD) a.k.a. pseudogout (blue = positively birefringent rhomboid crystals)
Clear yellow fluid, 200–300 WBCs, few neutrophils
Non-inflammatory (normal or OA)
Red fluid, 300–400 WBCs, 60% neutrophils
Hemarthrosis (possibly traumatic or anticoagulated patient)
Cloudy fluid, 125,000 WBCs, mostly neutrophils
Septic arthritis (very high WBC, mostly PMNs)
Clear yellow fluid, 5,000–6,000 WBCs, 70% neutrophils
Inflammatory arthritis (e.g., RA or crystal-induced)
T score = -2.2
Osteopenia (T-score between -1.0 and -2.5)
T score = -0.8
Normal (T-score above -1.0)
T score = -2.9
Osteoporosis (T-score ≤ -2.5)
Z score = -1.5
Below expected for age (Z-score < -2.0 is considered abnormal; -1.5 may warrant further evaluation in younger patients
Juvenile Idiopathic Arthritis DX TESTS
ESR, CRP, CBC, Ferritin ↑; RF and anti-CCP negative
Gout DX TESTS
Monosodium urate crystals (needle-shaped, yellow, negatively birefringent)
CPPD DX TESTS
Calcium pyrophosphate crystals (rhomboid, blue, positively birefringent)
Polymyositis DX TESTS
CPK, anti-Jo-1, ANA, aldolase
Systemic Lupus Erythematosus DX TESTS
ANA, anti-dsDNA, anti-Smith, Anti-RNP, SSA, SSB
Rheumatoid Arthritis DX TESTS
RF, anti-CCP, ESR, CRP
Psoriatic Arthritis DX TESTS
+/- RF, anti-CCP (rare), HLA-B27
CREST (Limited Scleroderma) DX TESTS
Anti-centromere, ANA
Polymyalgia Rheumatica DX TESTS
Elevated ESR, CRP, ANA negative, normal CPK
RF, anti-CCP
RA
What is a DEXA scan?
Dual-energy x-ray absorptiometry (DEXA) scan measures bone mineral density and is helpful in the evaluation of osteoporosis.
What are the common sites for a DEXA scan?
Lumbar spine, Hip, radius.
What are the screenings and indications for a DEXA scan?
Female > 65 years old, Males > 70 years old, Younger if risk factors, Non-traumatic fracture, Loss of height.
What is the T score used for in a DEXA scan?
Used for postmenopausal females and males > 50 years old.
>/= 1.0 is normal
< 1.0 - > -2.5 is osteopenic
</= -2.5 is osteoporosis
</= -2.5 with a fragility fracture is severe osteoporosis.
What is the Z score used for in a DEXA scan?
Used for premenopausal females, males < 50, and children.
</= -2.0 is below the expected range and a cause should be sought.