MSK

Question 1

what drug causes reactivation of latent TB

Answer 1

TNF alpha inhibitor (infliximab)

Question 2

tingling in pinky and ring finger

Answer 2

cubital (ulnar nerve compression in cubital fossa)

Question 3

necrotising fasciitis treatment

Answer 3

debridement, penicillin, clindamycin

Question 4

what DMARD causes interstitial pneumonitis

Answer 4

methotrexate

Question 5

what rheumatoid drug causes black tarry stools

Answer 5

NSAIDs

Question 6

what rheumatoid drug in nephrotoxic

Answer 6

penicillamine, gold

Question 7

visual loss, mouth and genital ulcers

Answer 7

behcets

Question 8

what hypersensitivity is RA

Answer 8

type IV

Question 9

describe osteoarthritis on X-ray

Answer 9

articular cartilage failure
asymmetrical
loss of joint space
osteophyte formation
subchondral sclerosis
subchondral cysts

Question 10

OA hands

Answer 10

heberdens nodes (DIP), Bouchards nodes (PIP)

Question 11

Tx carpal tunnel

Answer 11

corticosteroid injection, splint, workplace task modification, standard open carpal tunnel release, arthroscopic

Question 12

Tx cubital

Answer 12

splint, neurolysis, anterior transposition

Question 13

Tx dupuytren

Answer 13

radiation therapy, needle aponeurotomy, collagenase injection, surgery

Question 14

Which nerve gets damaged in arm pathology –
Cubital tunnel issues – ulnar nerve; Humeral shaft fractures risk the radial nerve;
Supracondylar fracture of the distal humerus can cause median nerve damage (carpal tunnel)

Question 15

Corticosteroids (e.g. prednisolone) can cause osteoporosis which often presents _____

Answer 15

with a Dowager’s hump due to multiple wedge fractures

Question 16

hydroxychloroquine SE

Answer 16

retinopathy

Question 17

Common peroneal nerve injury –

Answer 17

severe lateral knee pain with inability to move ipsilateral foot and generalised numbness following total knee replacement

Question 18

Systemic sclerosis, characterised by fibrosis, vascular alterations (Raynaud’s) and autoantibodies, —–ANTIBODY?

Answer 18

anticentromere

Question 19

identified by detection of anti-cardiolipin

Answer 19

antiphospholipid syndrome

Question 20

Typical x-ray features of seronegative arthritis –

Answer 20

sacro-iliac joint erosions, soft tissue swelling, irregular peri-articular new bone formation, pencil-in-cup deformity and spinal ligament ossification