MS

Question 1

CIS

Answer 1

Clinically isolated syndrome (CIS)
* refers to a single episode of neurological symptoms
suggestive of MS
* often, on investigation using MRI, evidence of
abnormality in the brain or spinal cord is found

Question 2

RRMS

Answer 2

characterized by unpredictable but clearly defined
- relapses during which new symptoms appear or existing
ones get worse
* in between relapses, recovery is complete or near
complete to pre-relapse function (remission)
* most common type of MS, 85% of people diagnosed with
MS have RRMS

Question 3

SPMS

Answer 3

follows a diagnosis of
RRMS
* over time distinct relapses and remissions become less
apparent and the disease begins to progress steadily,
sometimes with plateaus

Question 4

PPMS

Answer 4

Primary-progressive MS (PPMS) is characterized by a slow
- accumulation of disability, without defined relapses
* approximately 10% of people with MS

Question 5

main MS issues

optic, bladder, weaknessm balance, depression

Answer 5

optic
- nystgmus
- dipoplia
- optic neuritis

bladder
- urgency, frequenct, retention, infection

weakness
- fatugue,
- temperature can cause weakness

balance
- risk for falls

depresssion, axiety mood disorders

Question 6

MS pain

types of pain and tx

Answer 6

neuropathic pain
- demyelination in CNS

musculoskeletal pain
- abnormal stress on joints, ligaments, muscles

tx
disease modifying therapies
- reduce frequency and severity of relapses
- reduce lesions in the brain and spinal cord

relapse managment
- steroids
- help decrease severity

sympmo manament
- baclofen
- gabapentin
- cannabis
- botox