M2 recap Flashcards
sodium
what is it for? normal levels
Sodium (Na+)
- 136 to 145 mEq/L
Major ECF Cation
Necessary for
- maintain fluid levels
- prevents low blood pressure
- Helps muscles contract
- Sends nerve impulses throughout the body
hypernatremia
causes? manifestations, Tx
Hypernatremia: Serum Sodium Levels > 145 mEq/L
Caused
- Excessive Na intake,
- Diabetes insipidus, Renal Failure, Cushing Syndrome
- Causes hyperosmolality leading to cellular dehydration
Manifestations
- Confusion, low urinary output
- HTN, tachycardia
- Hyper-reflexia, muscle twitching
- seizures, coma
Treatment
- Correct fluid deficit (hypo or iso)
- Diuretics
- Monitor fluid balance
HypoNatremia
Caused by
-Excessive Na loss by Sweat, emesis, diarrhea,
- Renal dysfunction, Diuretics, GI loss
- H20 gain (dilution effect), Inappropriate use of hypotonic IV fluids
Manifestations
- Hypotension
- confusion, headache, lethargy, seizures
- decreased muscle tone, twitching, tremors
Treatment
- Hypertonic IVF
- Fluid restriction
- Diet
potassium
Potassium (3.5 to 5.1 mmol/L)
- Major ICF cation
Necessary for
- Transmission and conduction of nerve and muscle impulses
- Maintenance of cardiac rhythms
- Depolarizes and generates action potentials
- Low K is shown as a flat T wave in cardiac rhythm
- Regulates protein synthesis, and glucose use and storage
hyperkalemia
Causes
- Massive cell destruction (burns, tumour, severe infections)
- Shift from ICF to ECF
- Most common cause of renal failure
Manifestations
- Oliguria
- Renal failure
- Addison disease
- Bradycardia, irregular heart rhythm
- Cramping leg pain
- Abdominal cramping
Treatment
- Hold K intake (ie meds)
- Loop diuretics
- Force K from ECF to ICF by IV insulin or sodium bicarbonate, calcium gluconate IV.
- Dialysis
hypokalemia
Caused by
- Abnormal losses of K+ via the kidneys or gastrointestinal tract
- Magnesium deficiency
- Metabolic alkalosis
Manifestations
- Oliguria
- cardiac issues
- Weakness of respiratory muscles
- Decreased gastrointestinal motility
- Impaired regulation of arteriolar blood flow
Treatment
- Diet – potassium-rich foods
- KCl supplements orally or IV
calcium
normal levels and functions
Calcium (2.10 to 2.75 mmol/L)
- More than 99% combined with phosphorus and concentrated in skeletal system
- Only about 30% of the calcium from foods is absorbed in the GI tract.
Functions:
- Strong bones and teeth
- Blood clotting
- Muscle contraction
(even keeping a normal heartbeat)
- Nerve function
hypercalcemia
Caused by
- Hyperparathyroidism (two-thirds of cases)
- Cancer and malignant bone disease
- Vitamin D overdose
Manifestations
- Muscle weakness, decreased reflexes
- Decreased memory
- Behavioural changes: confusion, disorientation,
- Constipation, nausea and vomiting
Treatment
- Calcitonin
- Excretion of Ca with loop diuretic
- Oral fluids (3-4L per day)
- Hydration with isotonic saline infusion
- Dialysis
hypocalcemia
Caused by
- Renal failure
- Hypothyroidism
- Acute pancreatitis
- Alkalosis
Manifestations
- Positive Trousseau’s or Chvostek’s sign
- Laryngeal stridor
- Tingling around the mouth or in the extremities
Treatment
- Oral or IV calcium supplements
- Diet (calcium, vitamin D, protein)
- Anticipate tracheostomy (laryngeal spams)
magnesium
normal level, what is its use
Magnesium (serum 0.65 to 1.05 mmol/L)
- 50% to 60% contained in bone.
- Regulated by GI absorption and renal excretion
- Kidneys conserve magnesium in times of need and excrete excess
- metabolism of protein and carbohydrates
- Important for normal cardiac function
hypermagnesemia
Hypermagnesemia (>1.05 mmol/L)
Caused by
- Increased intake or ingestion of products containing magnesium when renal insufficiency or failure is present
- Renal failure
- Adrenal insufficiency
Manifestations
- Bradycardia, hypotension
- Respiratory and cardiac arrest
Treatment
- IV CaCl or calcium gluconate
- Fluids to promote urinary excretion
hypomagnesemia
Caused by
- alcoholism
- Fluid loss from gastrointestinal tract
- Prolonged parenteral nutrition without supplementation
- Diuretics
- DKA
Manifestations
- Skeletal muscle weakness
- Hyperactive deep tendon reflexes
- Numbness and tingling
- Painful muscle contractions
Treatment
- Diet
- Oral supplements
- Parenteral IV magnesium when severe
phosphorus
Phosphorus (serum 1.0 to 1.5 mmol/L)
Activates vitamins and enzymes
Forms ATP for energy supplies
Assists in cell growth and metabolism
Maintains acid-base balance
Maintains calcium homeostasis
hyperphosphetemia
Hyperphosphatemia (>1.5 mmol/L)
Caused by
- Renal failure
Manifestations
- Same as hypocalcemia
- Muscle cramps
- Perioral numbness and tingling
- Bone and joint pain
Treatment
- Phosphate binders (e.g. calcium acetate)
- Diet low in phosphorus
hypophosphatemia
Caused by
- Alcohol withdrawal
- Recovery from diabetic ketoacidosis
- TPN
Manifestations
- Decreased cardiac output
- Weak peripheral pulses
- Skeletal muscle weakness
Treatment
- Diet high in phosphorus
- Vitamin D Supplements
- Oral or IV calcium (e.g. calcium carbonate)
- Sodium phosphate
labs for fluid and electrolyte imbalances
- Common serum electrolytes Na, K, Cl
- Extended electrolytes: Ca, Mg, Phosphate
DKA
characteristics
Caused by profound deficiency of insulin
Characterized by
Hyperglycemia
Ketosis
Acidosis
Dehydration
Most likely occurs in type 1
s/s
Tachycardia
Orthostatic hypotension
Lethargy/weakness
managment of DKA
Emergency Management of DKA
Airway management
Oxygen administration
Correct fluid/electrolyte imbalance
IV infusion 0.45% or 0.9% NaCl
When blood glucose levels approach 14 mmol/L
5% dextrose added to the regiment
Potassium replacement
Sodium bicarbonate
hyperparathyroidism
hyperparathyroidism happens when the thyroid gland makes too much thyroid hormone.
manifestations
- elevated T3/T4
- bruit over thyroid
medication:
Propylthiouracil (PTU) therapy to block the synthesis of T3 and T4
Iodine (131I) therapy to destroy thyroid cells
Surgery (Thyroidectomy)
Check behind neck for drainage
Position in high- fowlers
Calcium gluconate at bedside
addisons disease
Adrenal insufficiency occurs when the adrenal glands don’t make enough of the hormone cortisol.
Cause
Sudden withdrawal from corticosteroids
Hypofunction of adrenal cortex
Lack of pituitary ACTH
Signs and Symptoms
- Hypovolemia, hypoglycemia
- Hyponatremia, hyperkalemia
- Postural hypotension
- Hyperpigmentation
treatment
- corticosteroid therapy
cushings
cause?manifestations? symtpoms?
Cause: Excess adrenal corticoid activity caused by adrenal, pituitary, or hypothalamus tumours (cortisol)
Symptoms
- Edema of lower extremities
- Abdominal striae
- Buffalo hump (fat deposits)
manifests as
- Hyperglycemia
- Hypernatremia
- Hypokalemia
- Increased plasma cortisol levels
gastritis
inflammatio of the gastric mucisa
- resulting in tissue edema which can cause a gastric hemorage
Clinical manifestations
Anorexia, Epigastric tenderness
Hemorrhage
Risk factors
Drug-related gastritis (ASA, corticosteroids)
Helicobacter pylori
burns , chrons disease, GERD, hernia
Vitamibn b12 deficiency
upper Gi bleed
80-85% spontaneously resolve
esophageal
- Varices
- Any types of drugs that irritate the esophagus
- Mallory weis tear
Stomach and duodenal origin (50% of all GI bleed)
- Cancer
- ulcers
appendicitis
what is it? manifestations? tx?
Often caused by an occlusion of the appendicile lumen or accumulation of feces, hypergrowth of lyphoid tissue, infection
Clinical manifestations
- Abdominal pain, the pain will radiate to the RLQ, lying still with right leg flexed
Nursing Management:
- NPO in case of surgery
- Pain control (opiods)
- heat is not advised because it may cause the appendix to rupture.
- The patient should be observed for evidence of peritonitis.
- Surgery