MRCP 2 Mocks Flashcards
Steroids and immunosuppression - how long?
Prednisolone 40 mg (or more) for longer than 7 days
Prednisolone 20 mg (or more) for longer than 14 days
Hypertriglyceridaemia - treatment
Fibrates
Livedo reticularis, skin ulceration and eosinophilia in a patient with atheromatous vascular disease who has recently started taking warfarin
Cholesterol embolisation
Pyoderma gangrenosum - initial treatment
PO Prednisolone
In the UK, ? is the most important current risk factor for recent hepatitis C virus infection
Intravenous drug use
Homosexual anal intercourse - which hepatitis?
Hepatitis B
Keratoderma blennorrhagica
Reactive Arthritis
Step up in Asthma management - Magnesium sulphate vs Aminophylline
Magnesium Sulphate first
Use of CMV-seronegative platelets is reserved for
Intrauterine and neonatal transfusions
Elective transfusion of pregnant women
Allogeneic haematopoietic stem cell transplant.
Rght upper quadrant pain, fever, and jaundice (Charcot’s triad) would point towards
Ascending Cholangitis
Investigation for iron deficiency (without anaemia) in postmenopausal women and men over the age of 50
Colonoscopy
Faecal occult blood testing is not particularly sensitive or specific.
Partial right bundle branch block
Elevation of the ST segment, leading to T-wave inversion in leads V1 and V2.
Brugada Syndrome
Definitive diagnostic test for pemphigus vulgaris
Direct immunofluorescence of skin
Asymptomatic, fine, scaly, reddish-brown, macular, coalescent rash over the upper trunk
Treatment?
Pityriasis versicolor
Itraconazole.
Treatment of macroprolactinoma
First-line treatment of these tumours is dopamine agonist therapy
Followed by surgery (usually transfrontal)
Normal pressure hydrocephalus - features
Urinary incontinence
Unsteadiness
Cognitive impairment.
Useful in exudative wounds
Alginate dressings
Wounds with signs of local infection
Antibacterial and silver-impregnated dressings
Meningitis complicating an ear infection
Streptococcus pneumoniae
Treatment for Herpes simplex meningo-encephalitis
Aciclovir
? for urate stones
Allopurinol
? reduces urinary calcium excretion
Bendroflumethiazide
? is for the treatment of cystinuria
Penicillamine
Transbronchial needle aspiration for what?
Sarcoidosis
Warfarin in pregnancy
Avoid
Primary hyperparathyroidism
vs
Familial benign hypocalciuric hypercalcemia
Urinary calcium excretion is high in Primary Hyperparathyroidism.
normotension, hypokalaemia + hypocalciuria
Gitelman’s syndrome
Ulnar deviation
Rheumatoid Arthritis
Mixed (type II) cryoglobulinaemia associated with
Hepatitis C
Urea breath test
H. pylori in the stomach.
Contraindications to infliximab in UC
Previous hepatitis B and previous tuberculosis
Azathioprine and ? have a severe interaction causing bone marrow suppression
Allopurinol
Treatment of choice for allergic bronchopulmonary aspergillosis
Oral glucocorticoids
First-choice agent for the treatment of hepatic encephalopathy
Lactulose
Secondary prophylaxis of hepatic encephalopathy
Lactulose and rifaximin
? can be used to help differentiate essential tremor from Parkinson’s
SPECT scan
Angioid retinal streaks
Ehlers-Danlos syndrome
The high-dose dexamethasone suppression test is useful for distinguishing between
ACTH dependent (e.g. pituitary source)
and
Non-ACTH dependent (e.g. ectopic and adrenal source) causes of Cushings’s syndrome
Ipsilateral CN III palsy and contralateral hemiparesis
Weber’s syndrome - form of midbrain stroke
Broad spectrum anti-emetic which blocks acetylcholine, dopamine, and serotonin receptors.
Levomepromazine
Convex ST segment in V1-V3 followed by a negative T wave
Brugada syndrome
T wave inversions in V1-3
Arrhythmogenic right ventricular dysplasia
Most useful agent in preventing the delayed phase of chemotherapy-induced emesis
Dexamethasone
Myelodysplasia may progress to ?
Acute myeloid leukaemia
? antibiotics are contraindicated in patients with myasthenia gravis due to the risk of myasthenic crisis
Aminoglycoside (Gent)
Refractory hypercalcaemia of malignancy may be treated with ? if therapy with fluids and pamidronate fails
Subcutaneous calcitonin
Toxic megacolon is seen in:
Ulcerative colitis
Multiple myeloma is a cause of ‘?’ amyloidosis
AL amyloidosis
Long-standing rheumatoid arthritis is a common cause of systemic ‘?’ amyloidosis
AA amyloidosis
Nitro or Trimethoprim in CKD?
Trimethoprim
? disease causes splenomegaly
Gaucher disease
Lysosomal storage disorder
? is the best way to differentiate between delirium and dementia
The Confusion Assessment Method (CAM)
Before a renal biopsy is performed, patients should have ?
Renal tract ultrasound
Schizotypal personality disorder
Social isolation and odd beliefs.
Bleeding patients with DIC and prolonged PT and aPTT
Fresh frozen plasma
Arrhythmogenic right ventricular cardiomyopathy - ECG
T wave inversion in V1-3
Brugada syndrome - ECG
Coved ST elevation in V1-3 followed by a negative T wave
Wellen’s syndrome - ECG
Biphasic T waves in V2-3
Chickenpox is a risk factor for invasive ? soft tissue infections including necrotizing fasciitis
Group A streptococcal
Chlamydia - treat with ?
Doxycycline
Gram-negative obligate intracellular pathogen - STI
Chlamydia
Cyanide poisoning
Hydroxycobalamin
Dicobalt Edetate
Sodium Thiosulphate
Sodium Nitrate
First line Ix for Acute chest syndrome (Sickle cell)
ABG
First line for Legionnaires
Macrolides
Treatment for Hairy Cell Leukaemia
Cladribine
Treatment of HSP
Usually supportive
Diagnostic test for Sarcoidosis
Tissue biopsy if possible
Safest epileptic in pregnancy
Lamotrigine
Chronic colonisation in CF with Pseudomonas
Prolonged Azithromycin
Agents used to maintain remission in Crohns
6-Mercaptopurine / Azathioprine
Treatment of Chagas
Benznidazole
Treatment of Schistosomiasis
Praziquantel
? is used to prevent vasospasm in aneurysmal subarachnoid haemorrhages
Nimodipine
? is the treatment of choice for an acute attack of neuromyelitis optica
IV methylprednisolone
Coil or clip for intracranial aneurysms
Coil
Treatment of choice for trigeminal neuralgia?
Carbamazepine