Motor system Flashcards

1
Q

Define a motor unit

A

alpha motor neuron and the muscle fibers it innervates

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2
Q

What is the size principle for recruitment of muscles?

A

small neurons have higher input resistances due to having fewer membrane channels –> brought to threshold with LESS synaptic input than larger motor neurons

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3
Q

what effect does exercise have on the motor unit?

A

shifts motor unit phenotype from fast to slow (slowed fatigability and increased endurance)

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4
Q

What provides muscles with resistance to fatigability?

A

increased numbers of mitochondria

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5
Q

compare sensory info encoded by muscle spindles and golgi tendon organs

A

Muscle spindles: stretch via group Ia and II sensory afferents

Golgi tendon organs: Tension via Ib afferents

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6
Q

Where are muscle spindles located?

A

PARALLEL to force-generating (extrafusal) muscle fibers

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7
Q

Where are golgi tendon organs located?

A

IN SERIES at junction of muscle and tendon

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8
Q

Describe muscle spindle motor neuron innervation

A

Gamma motor neurons (stretch detectors of contracted or relaxed muscle)

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9
Q

Describe golgi tendon organ motor neuron innervation

A

Type Ib sensory afferents are around/in collagen strands. Tension –> pinched afferents –> firing. Analogous to chinese finger trap

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10
Q

Describe muscle spindle interneuron innervation

A

Inhibitory interneuron –> relaxed antagonist muscle

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11
Q

Describe golgi tendon organ interneuron innervation

A

Inhibitory and excitatory interneuron synapses –> extensor-flexor coupling

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12
Q

Describe the basic stretch reflex

A

hammer tap –> muscle stretch –> muscle spindle firing –> alpha motor neuron activation (contracts stretched muscle), and inhibitory interneuron activation (relaxes antagonist muscle)

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13
Q

What is the basal firing rate of Ia afferents?

A

Non-zero. Can increase (in response to stretch) or decrease (in response to shortening) firing rates –> maintained muscle tone

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14
Q

What is the significance of coactivation of alpha and gamma motor neurons?

A

leads to co-contraction of extrafusal and intrafusal muscle fiber –> maintained spindle stretch sensitivity in shortened muscle

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15
Q

What is the physiological process at play when you lift an empty box labeled “books”?

A

Gamma motor neurons rapidly detect mismatches between expected and actual muscle stretch –> error correction (reduced muscle contraction)

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16
Q

Are gamma neurons active during reflexive contractions?

17
Q

What happens when you step on a tack?

A

cutaneous nociceptors –> spinal interneurons –> coordinated extensor relaxation and flexor contraction on side of stimulus; extensor contraction and flexor relaxation on opposite side

18
Q

What is meant by “hierarchical organization” of the motor system?

A

Motor system is increasingly flexible and more voluntary as neurons go from periphery to forebrain

19
Q

What are central pattern generators?

A

Spinal cord circuits that lead to the ability to generate complex coordinated movements like locomotion and swimming

20
Q

Describe the motor neuron somatotopy

A

Disproportionate M1 surface area to muscles involved in fine motor tasks. Mapping reflects MOVEMENTS, not muscles (not a true homunculus)

21
Q

Which alpha motor neurons control lateral musculature?

A

laterally situated motor neurons

22
Q

Which alpha motor neurons control medial musculature?

A

medially situated motor neurons

23
Q

Describe the descending pathway controlling finger movement

A

Precentral gyrus (Brodmann’s area 4) –> layer 5 pyramidal neurons –> internal capsule –> cerebral peduncle –> pons (collateralization) –> medulla (decussate) –> lateral corticospinal tract –> alpha motor neurons –> hand and finger movement

24
Q

Describe the descending pathway controlling movement of the axial musculature

A

Precentral gyrus (Brodmann’s area 4) –> layer 5 pyramidal neurons –> internal capsule –> cerebral peduncle –> pons (collateralization) –> medulla (no decussation) –> ventral corticospinal tract –> motor neuron pools –> axial and proximal limb muscles

25
How is plasticity involved in recovery from stroke?
areas adjacent to damage form new connections that subserve motor control over the affected part of the body. Can lead to full or partial functional recovery
26
Why do people say "practice makes perfect"?
Practice leads to expansion of involved cortical region (plasticity)
27
Describe the basic mechanism of brain-machine interfaces
Neural activity is recorded from the brain and decoded in the machine. Machine decipher's motor plan of action --> control of robotic limb