Chemosensation Flashcards

1
Q

taste receptor morphology

A

modified epithelial cell located inside a taste pore. Synapses on CN 7, 9, or 10 ganglion fiber

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2
Q

Conscious taste neural pathway

A

Taste bud –> cranial nerve –> solitary tract nucleus –> VPM thalamus –> insular cortex

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3
Q

role of trigeminal nerve in chemosensation

A

chemesthesis (detection of noxious stimuli). Free nerve ending of CN 5 ganglion cell –> SpV

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4
Q

smell receptor morphology

A

ciliated bipolar neurons

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5
Q

How is an odor identified?

A

via a recognized pattern of activity across olfactory glomeruli

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6
Q

What are the three types of gustatory papillae?

A

fungiform, foliate, circumvallate

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7
Q

Describe fungiform papillae

A

anterior portion of tongue. chorda tympani branch of CN 7 (anterior 2/3 of tongue)

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8
Q

Describe foliate papillae

A

on sides of tongue. CN 9 innervation

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9
Q

Describe circumvallate papillae

A

Posterior tongue. CN 9 innervation

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10
Q

Where are the taste receptors innervated by CN 10?

A

oropharynx

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11
Q

5 primary taste qualities

A

sweet, sour, salty, bitter, umami (savory, MSG)

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12
Q

Which taste qualities are transduced via ion channels?

A

salty and sour

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13
Q

Which taste qualities are transduced via GPCRs?

A

sweet, bitter, umami

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14
Q

Describe the orthonasal route of odorant access to olfactory epithelium

A

in through nostrils –> olfactory epithelium

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15
Q

describe the retronasal route of odorant access to olfactory epithelium

A

mouth –> oropharynx –> nasopharynx –> olfactory epithelium

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16
Q

Odor transduction pathway

A

Odorant binds receptor –> G protein activation –> cAMP –> influx of Na (depolarization) and Ca –> opened Ca-gated Cl channels –> Cl efflux –> further depolarization –> activated olfactory glomeruli

17
Q

Olfactory pathway for memory

A

olfactory bulb –> entorhinal cortex –> hippocampus –> memories

18
Q

Olfactory pathway for conscious perception of smell

A

Olfactory bulb –> piriform cortex –> orbitofrontal cortex –> conscious perception of smell

19
Q

Olfactory pathway for visceral reactions and homeostasis

A

Olfactory bulb –> olfactory tubercle and amygdala –> hypothalamus –> visceral reactions and homeostasis