Motor Neurone Disease Flashcards
1
Q
are males or females affected more
A
equal
2
Q
what percentage of MND is sporadic vs familial
A
sporadic 90%
familial 10%
3
Q
at what age does sporadic MND peak at?
A
50-75 years old
4
Q
what is the most common MND phenotype
A
Amyotrophic Lateral Sclerosis (ALS)
5
Q
is ALS more common in Caucasian or non-Caucasian populations
A
more common in Caucasian
6
Q
upper motor neurone features
A
spasticity
hyperreflexia
weakness
upgoing plantars
7
Q
lower motor neurone clinical features of MND
A
fasciculations
muscle atrophy (later on)
8
Q
are the eye and sphincter muscles generally affected early or late in the MND disease course?
A
late
9
Q
is there any sensory disturbance in MND
A
no
10
Q
A
