Motor neuron disease Flashcards
1
Q
MND presenting with pure LMN signs
Predominant UMN signs
A
Spinal muscular atrophy
Primary lateral sclerosis
2
Q
MOA of Riluzole
A
Sodium channel blocker that inhibits glutamate release
from presynaptic terminals, stabilises inactive state of voltage dependent Na chls
3
Q
Mutation in familial form of ALS
A
SOD-1
4
Q
Antibody in MMCB
A
Ig M anti-GM1 antibody
