Motor Neuron Disease

Question 1

What is Motor neurones disease?

Answer 1

A degenerative loss of cells from the motor cortext, the anterior horn or cranial nerve nuclei which does not affect sensory neurones or the sphincter. Never affects eye movements

Question 2

How does motor neurones disease present?

Answer 2

in >40s with loss of gait and aspiration pneumonitis. tongue fasiculations. No structural abnormailites are found on MRI

Question 3

How is Motor Neurones disease treated?

Answer 3

Riluzole is a antiglutamateric drug.

Symtoms control and psychological counselling

Question 4

How is Motor Neurones disease treated?

Answer 4

Riluzole is a antiglutamateric drug.

Symtoms control and psychological counselling

Question 5

What part of neuroanatomy is affected in motor neurones disease?

Answer 5

anterior horn cells

Question 6

What cognitive impairment is associated with motor neurones disease?

Answer 6

Frontotemporal dementia

leads to apathetic emotional change

Question 7

What are bulbar symptoms?

Answer 7

symptoms stemming from cranial nerves IX, X, XI and XII