Morphology 1° & 2° Lesions

Question 1

Primary Lesions

Definition

Answer 1

a de-novo initial lesion that has not been altered by trauma or manipulation, and has not regressed

Question 2

dried uid (serum, blood, or purulent exudate) originating from a lesion (e.g. impetigo)

Answer 2

crust

Question 3

: excess keratin (e.g. seborrheic dermatitis)

Answer 3

scale

Question 4

thickening of the skin and accentuation of normal skin markings (e.g. chronic atopic
dermatitis)

Answer 4

lichenification

Question 5

a linear slit-like cleavage of the skin

Answer 5

fissure

Question 6

a scratch mark

Answer 6

excoriation

Question 7

histological decrease in size or number of cells or tissues, resulting in thinning or depression of
the skin

Answer 7

atrophy

Question 8

a disruption of the skin involving the epidermis alone; heals without scarring

Answer 8

erosion

Question 9

a disruption of the skin that extends into the dermis or deeper; may heal with scarring

Answer 9

ulcer

Question 10

translate wheal

Answer 10

roncha

Question 11

define wheal

Answer 11

l: a special form of papule or plaque that is transient (<24 h) and blanchable, oen with a halo and
central clearing, formed by edema in the dermis (e.g. urticaria)

Question 12

comedone

Answer 12

a special collection of sebum and keratin

Question 13

kinds of comedone

Answer 13

■ open comedo (blackhead)

■ closed comedo (whitehead)

Question 14

define petechiae

Answer 14

pinpoint extravasation of blood into dermis resulting in hemorrhagic lesions; nonblanchable, <3 mm in size

Question 15

purpura

Answer 15

: larger than petechia, 3 mm-1 cm in size

Question 16

ecchymosis

Answer 16

larger than purpura, >1 cm in size (i.e. a “bruise”)

Question 17

telangiectasia:

Answer 17

dilated supercial blood vessels; blanchable, reticulated, and of small calibre, can be
associated with benign or malignant entities

Question 18

cyst:

Answer 18

an internally epithelial-lined structure containing semi-solid material or uid

Question 19

acral:

Answer 19

relating to the hands and feet (e.g. perniosis, secondary syphilis)

Question 20

annular:

Answer 20

ring-shaped (e.g. granuloma annulare)

Question 21

guttate:

Answer 21

lesions following a “drop-like” pattern (e.g. guttate psoriasis)

Question 22

• Koebner phenomenon:

Answer 22

i.e. isomorphic response, appearance of lesions at an injury site (e.g. lichen
planus, psoriasis, vitiligo)

Question 23

morbilliform:

Answer 23

literally means “measles-like”, an eruption composed of macules and papules with
truncal predominance

Question 24

reticular:

Answer 24

lesions following a net-like pattern (e.g. livedo reticularis)

Question 25

satellite:

Answer 25

small lesions scattered around the periphery of a larger lesion (e.g. candida diaper dermatitis)

Question 26

serpiginous:

Answer 26

lesions following a snake-like pattern (e.g. cutaneous larva migrans)

Question 27

target/targetoid:

Answer 27

concentric ring lesions, like a dartboard (e.g. EM)

Question 28

other descriptive terms

Answer 28

discrete, clustered, linear, conuent, dermatitic, indurated (i.e. hard or rm)