Drug Eruptions: Pustular Flashcards
1
Q
ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS (AGEP)
Clinical Feature
• morphology:
A
morphology: extensive erythematous, edematous, and sterile pustules
2
Q
AGEP systemic features
A
systemic features
high fever, leukocytosis with neutrophilia
3
Q
AGEP spread:
A
starts in face and intertriginous areas, spreads to trunk and extremities
4
Q
AGEP time course:
A
appears 1 wk after drug initiation, resolves 2 wk after withdrawal
5
Q
AGEP Epidemiology
A
• rare: 1-5/million
6
Q
AGEP • common causative agents:
A
• common causative agents: aminopenicillins, cephalosporins, clindamycin, calcium channel blockers
7
Q
AGEP Management
A
discontinue offending drug and systemic corticosteroids
