Morphine Sulfate Flashcards

0
Q

Drug Classification

A

Narcotic analgesic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

What is its 2nd Action?

A

Depresses CNS by interacting with opiate receptors in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is its 1st action?

A

Decreases pain perception & produces euphoria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is its 3rd action?

A

⬇️ ❤️ O2 demand by:

  • ⬇️ Preload by peripheral vasodilation causing venous pooling & ⬇️ venous return
  • ⬇️ Afterload by peripheral vasodilation causing ⬇️ systemic vascular resistance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

1st Indication

A

Moderate to Severe Pain

esp. Burns and fractures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

2nd Indication

A

CP of myocardial origin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

3rd Indication

A

Pulmonary Edema

Not in LA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Contraindications?

A
  1. Hypotension
  2. ⬆️ ICP - Head injury
  3. Pt’s at risk for Respiratory Depression (rate
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Adverse Effects

A
CARDIO-tachy, brady, hypotension 
RESP- bronchospasm, depression, apnea
NEURO- sedation-aloc, dizziness, agitation, tremors/seizures, hallucinations, blurred vision
G/I- n/v
OTHER- itching, flushed skin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Administration

A

Pain Control

2-10mg slow (2mg/min) IVP
Titrate to pain relief
May repeat IVP dose prn to max. 20mg

5-10mg IM single dose, no repeat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

PEDS

A

0.1mg/kg slow (1mg/min)
Titrate to pain relief

0.1 mg/kg IM single dose, no repeat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Onset

A

2-5 min. IVP

5-30 min. IM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Duration

A

3-4 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What other drug should be available and why?

A

Naloxone

Reverse resp. depression caused by morphine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why does morphine cause hypotension?

A

Histamine mediated hypotension

Volume depleted

Right Ventricular MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Use caution for these patients:

A

Sudden onset headache
Active Labor
Elderly
ETOH/Drugs

16
Q

How can morphine be mixed?

A

Mix 10mg (1mL) w/ 9ml of NS
To produce a concentration of
1mg / 1mL

17
Q

How is Morphine supplied?

A

4mg vial

10mg in 1 mL vial, pre-filled syringe or ampule

18
Q

What schedule is Morphine

A

Schedule II

19
Q

Reference #806

Isolated extremity injury/burn

A

Moderate to Severe pain
2-4mg slow IVP. Titrate to relief.
May repeat one time.

PEDS: 0.1mg/kg slow IVP
NO REPEAT
Max total dose 4mg

20
Q

Reference #806

Crush injury

A

2-12 mg slow IVP. Titrate to pain relief.
Max dose total 20mg

PEDS: 0.1mg/kg slow IVP
NO REPEAT
Max dose total 4mg