Morphine Sulfate Flashcards
Drug Classification
Narcotic analgesic
What is its 2nd Action?
Depresses CNS by interacting with opiate receptors in the brain
What is its 1st action?
Decreases pain perception & produces euphoria
What is its 3rd action?
⬇️ ❤️ O2 demand by:
- ⬇️ Preload by peripheral vasodilation causing venous pooling & ⬇️ venous return
- ⬇️ Afterload by peripheral vasodilation causing ⬇️ systemic vascular resistance
1st Indication
Moderate to Severe Pain
esp. Burns and fractures
2nd Indication
CP of myocardial origin
3rd Indication
Pulmonary Edema
Not in LA
Contraindications?
- Hypotension
- ⬆️ ICP - Head injury
- Pt’s at risk for Respiratory Depression (rate
Adverse Effects
CARDIO-tachy, brady, hypotension RESP- bronchospasm, depression, apnea NEURO- sedation-aloc, dizziness, agitation, tremors/seizures, hallucinations, blurred vision G/I- n/v OTHER- itching, flushed skin
Administration
Pain Control
2-10mg slow (2mg/min) IVP
Titrate to pain relief
May repeat IVP dose prn to max. 20mg
5-10mg IM single dose, no repeat
PEDS
0.1mg/kg slow (1mg/min)
Titrate to pain relief
0.1 mg/kg IM single dose, no repeat
Onset
2-5 min. IVP
5-30 min. IM
Duration
3-4 hours
What other drug should be available and why?
Naloxone
Reverse resp. depression caused by morphine
Why does morphine cause hypotension?
Histamine mediated hypotension
Volume depleted
Right Ventricular MI